The Bob Harrington Show

• Cardiology 2024 Highlights and Predictions for 2025

  Drs Harrington and Gibson review their picks for the top cardiology trials of 2024 and look ahead to 2025, particularly what health topics may be prioritized by the new administration. This podcast is intended for healthcare professionals only. To read a transcript or to comment https://www.medscape.com/author/bob-harrington Beta-Blockers after Myocardial Infarction and Preserved Ejection Fraction (REDUCE AMI) https://www.nejm.org/doi/abs/10.1056/NEJMoa2401479 Intensive Blood-Pressure Control in Patients with Type 2 Diabetes (BPROAD) https://doi.org/10.1056/nejmoa2412006 Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis EARLY TAVR https://www.nejm.org/doi/full/10.1056/NEJMoa2405880 Asundexian versus Apixaban in Patients with Atrial Fibrillation (OCEANIC-AF) https://doi.org/10.1056/NEJMoa2407105 In the Wake of OCEANIC-AF, Is Equipoise Regarding Factor XI Inhibition Still Afloat? https://www.jacc.org/doi/10.1016/j.jacc.2024.10.105 Preventive percutaneous coronary intervention versus optimal medical therapy alone for the treatment of vulnerable atherosclerotic coronary plaques (PREVENT): a multicentre, open-label, randomised controlled trial https://doi.org/10.1016/S0140-6736(24)00413-6 Preventive Coronary Stents: Not There Yet https://www.medscape.com/viewarticle/preventive-coronary-stents-not-there-yet-2024a10006yr Speech by Commissioner Robert M. Califf to the House of Medicine June 16, 2023 https://www.fda.gov/news-events/speeches-fda-officials/speech-commissioner-robert-m-califf-house-medicine-06162023 Evolution of Single-Lead ECG for STEMI Detection Using a Deep Learning Approach https://doi.org/10.1016/j.ijcard.2021.11.039 From ST-Segment Elevation MI to Occlusion MI: The New Paradigm Shift in Acute Myocardial Infarction https://doi.org/10.1016/j.jacadv.2024.101314 You may also like: Hear John Mandrola, MD’s summary and perspective on the top cardiology news each week, on This Week in Cardiology https://www.medscape.com/twic Questions or feedback, please contact [email protected]

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• Does ST-Elevation MI Need a Rebrand to ‘Occlusion MI’?

  A review paper prompted a discussion among cardiologists Bob Harrington, Manesh Patel, and Michael Gibson on whether the ST-segment elevation myocardial infarction paradigm needs an update. This podcast is intended for healthcare professionals only. To read a transcript or to comment, visit https://www.medscape.com/author/bob-harrington From ST-Segment Elevation MI to Occlusion MI: The New Paradigm Shift in Acute Myocardial Infarction https://doi.org/10.1016/j.jacadv.2024.101314 Angiographic and Clinical Outcomes Among Patients With Acute Coronary Syndromes Presenting With Isolated Anterior ST-Segment Depression: A TRITON-TIMI 38 Substudy https://doi.org/10.1016/j.jcin.2010.05.012 Treatment Time and In-Hospital Mortality Among Patients With ST-Segment Elevation Myocardial Infarction, 2018-2021 https://jamanetwork.com/journals/jama/fullarticle/2798440 Evolution of Single-Lead ECG for STEMI Detection Using a Deep Learning Approach https://doi.org/10.1016/j.ijcard.2021.11.039 Implantable Cardiac Alert System for Early Recognition of ST-Segment Elevation Myocardial Infarction https://doi.org/10.1016/j.jacc.2019.01.014 TIME Trial: Effect of Timing of Stem Cell Delivery Following ST-Elevation Myocardial Infarction on the Recovery of Global and Regional Left Ventricular Function: Final 2-Year Analysis https://doi.org/10.1161/CIRCRESAHA.117.311466 Early Versus Delayed Invasive Intervention in Acute Coronary Syndromes https://www.nejm.org/doi/full/10.1056/NEJMoa0807986 Translating AI for the Clinician https://doi.org/10.1001/jama.2024.21772 A Novel Breakthrough in Wrist-Worn Transdermal Troponin-I-Sensor Assessment for Acute Myocardial Infarction https://doi.org/10.1093/ehjdh/ztad015 A Phase 3 Study of Zalunfiban in Subjects With ST-elevation MI (CELEBRATE) https://clinicaltrials.gov/study/NCT04825743 Selatogrel Outcome Study in Suspected Acute Myocardial Infarction (SOS-AMI) https://clinicaltrials.gov/study/NCT04957719 You may also like: Hear John Mandrola, MD's summary and perspective on the top cardiology news each week, on This Week in Cardiology https://www.medscape.com/twic Questions or feedback, please contact [email protected]

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• Cardiovascular Disease 2050: No, GLP-1s Won't Save the Day

  Cardiologists Bob Harrington and Dhruv Kazi discuss the projected burden of cardiovascular disease in 2050, why it's not sustainable, and what can be done to prevent it. This podcast is intended for healthcare professionals only. To read a transcript or to comment, visit https://www.medscape.com/author/bob-harrington INCLUDE URLS and full titles for some of the pertinent studies cited. Forecasting the Burden of Cardiovascular Disease and Stroke in the United States Through 2050 https://doi.org/10.1161/CIR.0000000000001256 Forecasting the Economic Burden of Cardiovascular Disease and Stroke in the United States Through 2050 https://doi.org/10.1161/CIR.0000000000001258 Calculating the 30-day Survival Rate in Acute Myocardial Infarction: Should we Use the Treatment Chain or the Hospital Catchment Model? https://doi.org/10.5301/heartint.5000238 Life's Essential 8: Updating and Enhancing the American Heart Association's Construct of Cardiovascular Health https://doi.org/10.1161/CIR.0000000000001078 Current Trends in Hypertension Identification and Management: Insights from the National Health and Nutrition Examination Survey https://doi.org/10.1161/JAHA.123.034322 Youth-Onset Type 2 Diabetes: The Epidemiology of an Awakening Epidemic https://doi.org/10.2337/dci22-0046 US Trends in Cholesterol Screening, Lipid Levels, and Lipid‐Lowering Medication Use in US Adults, 1999 to 2018 https://doi.org/10.1161/JAHA.122.028205 GLP-1 Receptor Agonist Discontinuation Among Patients With Obesity and/or Type 2 Diabetes https://pubmed.ncbi.nlm.nih.gov/38787563 Health Care by Food https://healthcarexfood.org/ You may also like: Hear John Mandrola, MD's summary and perspective on the top cardiology news each week, on This Week in Cardiology https://www.medscape.com/twic Questions or feedback, please contact [email protected]

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• From Fact to Fiction: Medical Journalist–Turned-Author

  Dr Bob Harrington interviews journalist Shelley Wood about her new book, "The Leap Year Gene of Kit McKinley," her creative process, and the difference between medical journalism and writing fiction. This podcast is intended for healthcare professionals only. To read a transcript or to comment, visit https://www.medscape.com/author/bob-harrington The Leap Year Gene of Kit McKinley https://shelleywood.ca/the-leap-year-gene/ Tragedy and Hope Wrapped in a Medical Mystery: Abraham Verghese and The Covenant of Water https://www.medscape.com/viewarticle/991751 You may also like: Hear John Mandrola, MD's summary and perspective on the top cardiology news each week, on This Week in Cardiology https://www.medscape.com/twic Questions or feedback, please contact [email protected]

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• Private Equity in Medicine: Cardiology in the Crosshairs

  Medical practices are increasingly being acquired by private equity. Bob Harrington discusses why and what the ramifications are with the authors and editorialist of a research paper on the private equity landscape in cardiology vs other specialties. This podcast is intended for healthcare professionals only. To read a transcript or to comment, visit https://www.medscape.com/author/bob-harrington Private Equity Acquisitions of Outpatient Cardiology Practices in the United States, 2013-2023 https://doi.org/10.1016/j.jacc.2024.06.011 Private Equity in Cardiovascular Practice: Solution or Symptom? https://doi.org/10.1016/j.jacc.2024.06.012 Evaluating Trends in Private Equity Ownership and Impacts on Health Outcomes, Costs, and Quality: Systematic Review https://doi.org/10.1136/bmj-2023-075244 2020 American Heart Association and American College of Cardiology Consensus Conference on Professionalism and Ethics: A Consensus Conference Report https://doi.org/10.1161/CIR.0000000000000963 You may also like: Hear John Mandrola's, MD, summary and perspective on the top cardiology news each week, on This Week in Cardiology https://www.medscape.com/twic Questions or feedback, please contact [email protected]

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