NEJM This Week

This week, we feature new research on preventing venous thromboembolism after hip or knee arthroplasty, antiplatelet therapy for acute coronary syndromes, and treatment for IgA nephropathy. We review advances in malaria prevention and follow a case of recurrent cardiomyopathy. Perspectives explore AI surveillance, equity in maternal–fetal medicine, and the challenges and rewards of medical training.

This week, we feature new research on obesity treatment, coronary imaging for acute chest pain, triglyceride lowering, and studies of silent atherosclerosis and IgA nephropathy. We review advances in stroke treatment, follow a challenging diagnostic case, and Perspectives explore health insurance profits, learning health systems, and the emotional challenges of caring for a seriously ill child.

This week, we feature new research on renal-replacement therapy for acute kidney injury, cardiac monitoring for unexplained syncope, and treatments for COPD and type 2 diabetes. We review antibiotic resistance in gram-negative bacteria and follow a complicated case of hemorrhage during pregnancy. Perspectives explore health care regulation, access to reproductive care, and the deeply personal decisions surrounding end-of-life care.

This week, we feature new research on antithrombotic therapy after acute coronary syndrome, treatments for Sjögren’s disease and infective endocarditis, and a new therapy for small-cell lung cancer. We review advances in H. pylori infection, follow a case of vision loss, and report on innovations in hemophilia treatment, clinical research ethics, clinical trial prediction markets, payment models in primary care, Medicaid policy, and trust in medicine.

This week, we feature new research on gene editing for hereditary angioedema, a chemotherapy-free approach to acute lymphoblastic leukemia, and treatments for ulcerative colitis and HIV. We review adult ADHD and follow a challenging case involving a spinal mass. We report on lung cancer screening, and Perspectives explore care interventions for older adults, access to fertility care, and the evolving role of AI in medicine.