Dr Karan Explores

OG Podcasts
Dr Karan Explores
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98 episodios

  • Dr Karan Explores

    How Food Builds Your Brain: Cooking Special with The Brain Docs

    30/03/2026 | 1 h 15 min
    Cooking isn’t just about flavour, it directly impacts your brain, gut, and heart health.

    In this special episode, Dr Karan teams up with The Brain Docs, Drs. Ayesha & Dean Sherzai, to cook a nutrient-dense curry while breaking down the real science behind food and its impact on your body. From fibre and omega-3s to anti-inflammatory ingredients and the gut-brain connection.
    Discussed in the episode:
     “the basic everyday food you eat literally makes your brain.”
     “what happens in your gut determines everything.”
    This is not about “superfoods”, it’s about dietary patterns, real ingredients, and how what you eat daily shapes your long-term health.
     What You’ll Learn:

    How food impacts brain function and mental health
    Why fibre is critical for your gut and brain
    The truth about tofu, coffee, and mushrooms
    Why “anti-inflammatory diets” actually matter
    The gut-brain connection explained simply
    How cooking methods affect nutrition
    Anti-inflammatory curry paste
    Tofu (high-protein, low saturated fat)
    Fibre-rich vegetables
    Ginger, garlic, turmeric & spices
    Cashew cream alternative to coconut milk

     What We Cook:

    Anti-inflammatory curry paste
    Tofu (high-protein, low saturated fat)
    Fibre-rich vegetables
    Ginger, garlic, turmeric & spices
    Cashew cream alternative to coconut milk

    Chapters:
    00:00:30 – Intro
    00:03:29 – “What happens in the gut determines everything”
    00:04:24 – Tofu as the protein + the soy myth
    00:06:51 – Coffee & cognition: What the data suggests
    00:11:20 – Ginger for nausea & gut motility
    00:12:36 – Dietary patterns over single foods (Mediterranean-style pattern explained)
    00:16:55 – “Eat the rainbow”: Polyphenols, fibre types, carotenoids
    00:19:29 – Omega-3 index & omega-3s as brain building blocks
    00:20:19 – Omega-3 supplements: When it’s reasonable
    00:22:23 – Prevention & the “pillars” analogy for long-term brain health
    00:35:42 – Mental health & the gut: It’s multi-layered
    00:36:24 – IBS: treating gut symptoms and mental health burden
    00:48:01 – Turmeric for brain health & research background
    00:49:20 – Turmeric supplements: Why high-dose curcumin is different from food
    01:06:12 – “Taste and adjust”: The most important cooking step before serving
    01:08:55 – Basil at the end & final flavour check
    01:09:20 – Curry ready
    01:12:50 – Dessert reveal: Chia pudding with cashews & mango
    01:22:08 – Final thoughts
  • Dr Karan Explores

    Warning Signs of Endometriosis Doctors Miss (Carla Cressy’s Story)

    23/03/2026 | 43 min
    Endometriosis red flags are often missed, especially when symptoms look like IBS, bladder issues, or “normal” test results.In this episode of Dr Karan Explores, Dr Karan Rajan speaks with Carla Cressy about her lived experience of endometriosis, the long road to diagnosis, what severe disease can look like, and how to advocate for yourself when you’re being dismissed.In this conversation, we cover:Warning signs doctors often miss (bowel/rectal pain, bladder/UTI-like symptoms, bleeding after sex, severe fatigue)Why endometriosis can be mislabelled as IBS/IBDWhy normal blood tests/scans don’t necessarily rule endometriosis out — and what to do nextThe impact on mental health, work, relationships, and quality of lifeFertility and access: egg freezing, NHS gaps, and why pathways matterPractical advocacy: symptom diaries, bringing someone to appointments, asking for documentation, and next-step questions to move care forwardAbout Dr Karan: Dr. Karan Rajan is a doctor, author, and educator dedicated to making health and medical science accessible to all. Through evidence-based analysis, he addresses topics such as gut health, brain health, and healthy lifestyle choices, while dispelling common medical myths with a touch of dark humor.🚽 Discover Throne’s incredible new smart toilet device at http://thronescience.com 🔥 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe🔥 For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: https://geni.us/DrKaranBook 📕 Pre-order my new book, This Is Vital Information, here: https://linktr.ee/ThisisVitalInformation?utm_source=linktree_profile_share&ltsid=472cbbde-00e2-42ab-8a3f-725656fab3a5🔥 Head to https://loamscience.com/ try LOAM - and get an additional 10% with code POD10.🤖 Discover my digital twin here: http://DrKaran.ai 📱Connect with me:Instagram: / drkaranrajanFacebook: / drkaranTikTok: / dr.karanrX: / drkaranrajanWebsite: www.drkaranrajan.com
  • Dr Karan Explores

    You’re Missing THIS About Eye Health | Dr Bryce Appelbaum

    19/03/2026 | 42 min
    💬 Vision and eyesight are two totally different things. And most of us are ignoring both! But improving your eye health is really easy when you know how. Not only can simple techniques help you stave off myopia, they can even improve your whole experience of the world.
    ⚡To discuss the art of vision training - and why it’s so crucial for all of us - Dr Karan is joined by Dr Bryce Appelbaum, Neuro-optometrist and CEO of MyVisionFirst. Whether you want to optimise your vision, or correct annoying issues, this conversation is for you.
    🎧 Stay tuned to find out:
    ➡ The difference between eyesight and vision - and why it’s important to separate them
    ➡︎ How even “perfect” eyesight can be optimised
    ➡︎ What screens are actually doing to our eyes
    ➡︎ Simple exercises to reduce common eye problems
    ➡︎ What happens when eye problems go unnoticed or are misdiagnosed
    ➡︎ How vision problems can mimic symptoms of ADHD and dyslexia
    #DrKaran, #MedicalScience, #HealthEducation, #HealthTips, #MedicalScience, #EyeSight, #EyeCare, #VisionTraining, #EyeHealth
    Don't miss an episode! Subscribe NOW: https://www.youtube.com/@DrKaran?sub_confirmation=1 
    📕 Chapters
    (0:00) Introduction - The difference between “vision” and “eyesight”
    (1:25) The eye-brain connection
    (2:56) How vision is really measured
    (4:39) Bringing vision back to a 92-year-old
    (9:38) Can “perfect” eyesight may be hiding real problems
    (12:09) Why cases of myopia/nearsightedness is rising
    (15:10) How to alleviate damage from screen-time
    (17:44) Signs you eyes have had too much screens
    (20:12) Simple tricks to alleviate common eye problems
    (24:18) The problem of misdiagnosed vision problems
    (26:52) How vision problems can mimic symptoms of ADHD and dyslexia
    (32:24) How often kids’ vision problems are being missed
    (35:46) Other environmental issues that affect vision
    (39:25) Two things you should start today for better eye health
    🚽 Discover Throne’s incredible new smart toilet device at http://thronescience.com 
    🤖 Discover my digital twin here: http://DrKaran.ai 
    🔥  Head to https://loamscience.com/ try LOAM - and get an additional 10% with code POD10.
    🔥 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe
    🔥 For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: https://geni.us/DrKaranBook 
    📕 Pre-order my new book, This Is Vital Information, here: https://linktr.ee/ThisisVitalInformation?utm_source=linktree_profile_share<sid=472cbbde-00e2-42ab-8a3f-725656fab3a5
    🎙️ An OG Podcasts production.
    About Dr Karan:
    Dr. Karan Rajan is a doctor, author, and educator dedicated to making health and medical science accessible to all. Through evidence-based analysis, he addresses topics such as gut health, brain health, and healthy lifestyle choices, while dispelling common medical myths with a touch of dark humor. His content provides reliable, research-driven insights designed to inform and empower viewers to better understand their health.
    📱Connect with me:
    Instagram: https://www.instagram.com/drkaranrajan/   
    Facebook: https://www.facebook.com/DrKaranR/  
    TikTok: https://www.tiktok.com/@dr.karanr  
    X: https://twitter.com/drkaranrajan  
    Website: https://linktr.ee/ThisisVitalInformation
  • Dr Karan Explores

    Can Psychedelics Reset a Depressed Brain?

    16/03/2026 | 54 min
    Can psilocybin treat depression within a day? In this episode, Dr Karan Rajan sits down with psychedelic researcher Dr Rayyan Zafar to break down the science of psilocybin, treatment-resistant depression, brain scans, microdosing, and whether psychedelic therapy could become a real part of mainstream mental health care.
    They explore why current antidepressants do not work for everyone, how psychedelics may affect the brain differently, what researchers are seeing on scans after a single dose, and why the conversation around psychedelic therapy is far more nuanced than internet hype suggests.
    In this episode:

    Why psychiatry needs new tools for depression
    Why SSRIs do not work for everyone
    How psilocybin interacts with serotonin receptors
    The idea of a “plastic window” after psychedelic therapy
    Whether psychedelics could help healthy people, not just patients
    What the evidence says about microdosing
    The real safety questions around psychedelic treatment
    DMT, short-acting psychedelics, and where the field may go next

    00:00 - Welcome Dr Rayyan Zafar
    04:35 - How psychedelics work in the brain
    07:29 - Psychedelics, culture and meaning-making
    08:21 - What counts as treatment-resistant depression?
    15:26 - Could psychedelics become preventative medicine?
    17:20 - Depression, rumination and the default mode network
    20:37 - The “plastic window” and why therapy matters
    26:09 - The truth about Microdosing
    33:20 - Safety, screening and who should avoid psychedelics
    42:04 - DMT, ayahuasca and future treatments
    44:04 - Why short-acting psychedelics matter
    About Dr Karan:
    Dr. Karan Rajan is a doctor, author, and educator dedicated to making health and medical science accessible to all. Through evidence-based analysis, he addresses topics such as gut health, brain health, and healthy lifestyle choices, while dispelling common medical myths with a touch of dark humor.

     🚽 Discover Throne’s incredible new smart toilet device at http://thronescience.com
    🔥 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe
    🔥 For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: https://geni.us/DrKaranBook
    📕 Pre-order my new book, This Is Vital Information, here: https://linktr.ee/ThisisVitalInformation?utm_source=linktree_profile_share&ltsid=472cbbde-00e2-42ab-8a3f-725656fab3a5
    🔥 Head to https://loamscience.com/ try LOAM - and get an additional 10% with code POD10.
    🤖 Discover my digital twin here: http://DrKaran.ai

    Connect with me:
    Instagram: / drkaranrajan
    Facebook: / drkaran
    TikTok: / dr.karanr
    X: / drkaranrajan
    Website: www.drkaranrajan.com
    #Psilocybin #MentalHealth #Neuroscience #PsychedelicTherapy #healthpodcast
  • Dr Karan Explores

    The Science of Eating at the Right Time | Adriano dos Santos

    12/03/2026 | 49 min
    💬 Health isn’t just about what you eat - it’s about when. Meal timing matters much more than you might realise. The same food eaten at different times can have wildly different effects on your body. 
    ⚡To discuss the emerging field of chrononutrition, Dr Karan is joined by Adriano dos Santos - known as The Circadian Nutritionist. Together they explain how your organs and even your gut microbiome keep time - operating on a circadian clock!
    🎧 Stay tuned to find out:
    ➡ How clock genes throughout our entire body impact our health
    ➡︎ Why poor meal timing can create a lack of energy, sleep struggles and even IBS
    ➡︎ How late nate phone scrolling isn’t as bad as you think
    ➡︎ Why late night snacking and evening exercise confuses your body clock
    ➡︎ Why not all fasting is created equal
    ➡︎ Which foods and habits will improve your health and body clock the fastest
    #DrKaran, #MedicalScience, #HealthEducation, #HealthTips, #MedicalScience, #MealTiming, #ChronoNutrition, #CircadianNutrition, #DietTips, #GutHealth,
    Don't miss an episode! Subscribe NOW: https://www.youtube.com/@DrKaran?sub_confirmation=1 
    📕 Chapters
    (0:00) Introduction - Why chrono nutrition is so important for health
    (02:15) The health impacts of not paying attention to meal timing
    (04:46) How  butyrate interacts with your internal clock
    (06:56) What happens when your gut timing is out of sync
    (10:35) The gut clock’s role in sleep
    (14:37) How late night phone scrolling impacts your body clock
    (18:40) Should you avoid late night snacking?
    (21:58) How the same calories affect you differently depending on when you eat them
    (26:26) Should you eating your fibre earlier in the day?
    (31:19) Why fasting might not be as healthy as we thought
    (36:09) How body clock disruption could cause IBS
    (40:12) Specific food and habits to improve
    🚽 Discover Throne’s incredible new smart toilet device at http://thronescience.com 
    🔥 Get my free weekly newsletter filled with easy to action health tips, interesting facts and science to fill your curiosity: https://drkaran.beehiiv.com/subscribe
    🔥 For more useful science for your everyday life, grab my best selling book “This Book May Save Your Life”: https://geni.us/DrKaranBook 
    📕 Pre-order my new book, This Is Vital Information, here: https://linktr.ee/ThisisVitalInformation?utm_source=linktree_profile_share
    🔥  Head to https://loamscience.com/ try LOAM - and get an additional 10% with code POD10.🤖 Discover my digital twin here: http://DrKaran.ai
    🎙️ An OG Podcasts production.
    About Dr Karan:
    Dr. Karan Rajan is a doctor, author, and educator dedicated to making health and medical science accessible to all. Through evidence-based analysis, he addresses topics such as gut health, brain health, and healthy lifestyle choices, while dispelling common medical myths with a touch of dark humor. His content provides reliable, research-driven insights designed to inform and empower viewers to better understand their health.
    📱Connect with me:
    Instagram: https://www.instagram.com/drkaranrajan/   
    Facebook: https://www.facebook.com/DrKaranR/  
    TikTok: https://www.tiktok.com/@dr.karanr  
    X: https://twitter.com/drkaranrajan  
    Website: https://linktr.ee/ThisisVitalInformation

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Join Dr Karan as he meets the world's foremost experts in science and medicine to cut through the BS of modern health advice. Get my free weekly newsletter filled with easy to action health tips, interesting facts & science to fill your curiosity: https://drkaran.beehiiv.com/subscribe
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