Live Well Be Well with Sarah Ann Macklin | Health, Lifestyle, Nutrition

This week I'm joined by Dr Jack Kreindler, physician, healthtech entrepreneur and founder of WellFounded Health and the Centre for Health and Human Performance, and someone who has spent 26 years asking one of the most important questions in medicine, what does it mean to not just fix disease, but to truly enhance human life?
We explore longevity, prevention, performance and what the most advanced medicine in the world is learning about how to live well for longer.
Dr Jack Kreindler qualified in medicine and physiology from University College London and spent a decade as an emergency physician before founding the Centre for Health and Human Performance in Harley Street in 2007. He is an honorary clinical research fellow at Imperial College London, founder and CEO of WellFounded Health and a leading voice on healthy longevity, human performance and the future of medicine. He has worked with elite athletes, extreme environment explorers and high performance executives across the world.
What we explore together:
Why medicine is shifting from fixing disease to enhancing physiology and what that means for you

What burning the candle at three ends is actually doing to your brain and body

Why cadence is king and how everything in nature and biology moves in waves

What the most advanced health testing actually looks like and what it tells us

The truth about longevity supplements, peptides and biohacking and who they actually work for

Why your history is still the most powerful diagnostic tool ever invented

What it really means to enhance a human life rather than just extend it

Love, Sarah Ann 💛
My book 'Healthy Shouldn't Be This Hard': https://www.amazon.co.uk/Healthy-Shouldnt-Be-This-Hard-ebook/dp/B0G1DHNRV5
This episode is sponsored by:NOWATCH: The compassionate health tracker Connecting body and mind with unique stress recovery insights so you can live fully today👉 15% off with code LWBW15 at https://nowatch.com/
PULSETTO: Vagus nerve stimulation for stress, sleep and calm👉 Use code SARAHANN at https://pulsetto.sjv.io/SARAHANN
The Great British Veg OutHow to support your gut, energy, and hormones by eating more, not less.👉 https://sarahmacklin.substack.com/p/t…
Reset Your HealthIf your body feels off after stress, travel, or burnout, this is where to start.👉 https://sarahmacklin.substack.com/s/r...
👉 Practical beats perfect. Here's a free 5-recipe PDF I use to support energy and stress during busy weeks.https://sarahannmacklin.com/5_free_recipes
👉 If this resonates, you can join the thousands who read The Compassionate Cure each week.https://sarahmacklin.substack.com/
Let's be friends!📷 Instagram: https://www.instagram.com/sarahannmacklin/📹 Subscribe: https://youtube.com/@livewellbewellsarah🐦 Twitter: https://x.com/SarahAnnMacklin📱 TikTok: https://www.tiktok.com/@livewellbewellpodcast💌 Newsletter: https://sarahmacklin.substack.com/
Chapters
00:00 Introduction
02:59 How Jack's view of medicine changed over 26 years
05:58 Burning the candle at three ends and what it costs you
09:04 Why cadence is king in biology and life
12:00 What a prevention first approach to health looks like
18:00 Your history from one cell to 38 trillion
21:02 What advanced health testing actually reveals
30:00 Hormones, menopause and andropause
33:02 Cardiovascular risk and how to assess it properly
36:00 Brain health, dementia risk and what you can do now
39:07 The gut microbiome and its role in everything
42:00 Extreme environments and what they teach us about health
45:08 Elite sport science applied to everyday health
48:00 The longevity space and what the evidence actually shows
51:07 Peptides, supplements and biohacking
54:06 What works, what doesn't and how to know the difference
57:07 AI and the future of personalised medicine
66:04 The bell shaped curve and why nothing works for everyone
69:08 What enhancing a human life really means
72:00 Not dying dull and what Jack has learned
75:02 Final thoughts on living well and being well

This week's Live Well Be Well Moment with Cindy Gallop, advertising icon, entrepreneur and founder of Make Love Not Porn.
We delve into why Cindy has never wanted marriage or children, what dating younger men has taught her, and the one filter she applies to every person she dates — that most people never even think to use.
My book 'Healthy Shouldn't Be This Hard': https://www.amazon.co.uk/Healthy-Shouldnt-Be-This-Hard-ebook/dp/B0G1DHNRV5
This episode is sponsored by:
NOWATCH: The compassionate health tracker Connecting body and mind with unique stress recovery insights so you can live fully today. 👉 15% off with code LWBW15 at https://nowatch.com/
PULSETTO: Vagus nerve stimulation for stress, sleep and calm
👉 Use code SARAHANN at https://pulsetto.sjv.io/SARAHANN
More from me: The Great British Veg Out How to support your gut by eating more, not less https://sarahmacklin.substack.com/p/t…
Reset Your Health If your body feels off after stress, travel, or burnout, this is where to start! https://sarahmacklin.substack.com/s/r...
Free 5-recipe PDF for busy weeks https://open.substack.com/pub/sarahma...
Join thousands reading The Compassionate Cure → https://sarahmacklin.substack.com/
Let's be friends!
📷 Instagram https://www.instagram.com/sarahannmacklin 
📹 Subscribe https://youtube.com/@livewellbewellsarah?si=UbuuWvMjAcTkELPN 
📱 TikTok https://www.tiktok.com/@livewellbewellpodcast?_r=1&_t=ZN-96iOW29jTRm

This week's Live Well Be Well Moment with Cindy Gallop, advertising icon, entrepreneur and founder of Make Love Not Porn.
We delve into why Cindy built the world's first social sex video sharing platform, what porn culture is doing to real world relationships, and what happens when couples finally see what real sex actually looks like.
My book 'Healthy Shouldn't Be This Hard': https://www.amazon.co.uk/Healthy-Shouldnt-Be-This-Hard-ebook/dp/B0G1DHNRV5
This episode is sponsored by:
NOWATCH: The compassionate health tracker Connecting body and mind with unique stress recovery insights so you can live fully today. 👉 15% off with code LWBW15 at https://nowatch.com/
PULSETTO: Vagus nerve stimulation for stress, sleep and calm
👉 Use code SARAHANN at https://pulsetto.sjv.io/SARAHANN
More from me: The Great British Veg Out How to support your gut by eating more, not less https://sarahmacklin.substack.com/p/t…
Reset Your Health If your body feels off after stress, travel, or burnout, this is where to start! https://sarahmacklin.substack.com/s/r...
Free 5-recipe PDF for busy weeks https://open.substack.com/pub/sarahma...
Join thousands reading The Compassionate Cure → https://sarahmacklin.substack.com/
Let's be friends!
📷 Instagram https://www.instagram.com/sarahannmacklin 📹 Subscribe https://youtube.com/@livewellbewellsarah?si=UbuuWvMjAcTkELPN 
📱 TikTok https://www.tiktok.com/@livewellbewellpodcast?_r=1&_t=ZN-96iOW29jTRm

Warning ⚠️ This episode contains strong language

This week I'm joined by Fat Tony, DJ, author and one of the most honest voices in British culture on addiction, identity and what it really means to find yourself after years of hiding.
We explore recovery, relationships, shame and what happens when you finally stop performing and start living.
Fat Tony is one of the UK's most iconic DJs, having shaped the sound of London's club scene for over three decades. He is the author of I Don't Take Requests, a raw and honest memoir about addiction, shame, sexuality and recovery. Known for his sharp wit and unapologetic honesty, Tony has become one of the most compelling voices on mental health, sobriety and self acceptance in British public life. He knows what it means to lose yourself completely and to find your way back.
What we explore together:
Why acceptance is so much more powerful than tolerance and what the difference really means

Why addiction is never really about the substance and what we are actually trying to fix

How Tony went from one addiction to another without realising it

What happened when Tony finally let love in and why he had always avoided it

The therapy breakthrough that changed everything and what his attraction patterns were really telling him

What Tony would say to anyone who feels like they have given up hope

Why Tony says he has never been happier in his life and what it took to get there

Love, Sarah Ann 💛
My book 'Healthy Shouldn't Be This Hard': https://www.amazon.co.uk/Healthy-Shouldnt-Be-This-Hard-ebook/dp/B0G1DHNRV5
This episode is sponsored by:NOWATCH: The compassionate health tracker Connecting body and mind with unique stress recovery insights so you can live fully today👉 15% off with code LWBW15 at https://nowatch.com/
PULSETTO: Vagus nerve stimulation for stress, sleep and calm👉 Use code SARAHANN at https://pulsetto.sjv.io/SARAHANN
The Great British Veg OutHow to support your gut, energy, and hormones by eating more, not less.👉 https://sarahmacklin.substack.com/p/t…
Reset Your HealthIf your body feels off after stress, travel, or burnout, this is where to start.👉 https://sarahmacklin.substack.com/s/r...
👉 Practical beats perfect. Here's a free 5-recipe PDF I use to support energy and stress during busy weeks.https://sarahannmacklin.com/5_free_recipes
👉 If this resonates, you can join the thousands who read The Compassionate Cure each week.https://sarahmacklin.substack.com/
Let's be friends!
📷 Instagram: https://www.instagram.com/sarahannmacklin/
📹 Subscribe: https://youtube.com/@livewellbewellsarah🐦 Twitter: https://x.com/SarahAnnMacklin
📱 TikTok: https://www.tiktok.com/@livewellbewellpodcast
💌 Newsletter: https://sarahmacklin.substack.com/

This week's Live Well Be Well Moment with Dr David Rock, neuroscientist, author and founder of the NeuroLeadership Institute.
We delve into why everything in life is processed by the brain as either a threat or a reward, why being left out hurts as much as physical pain, and what understanding this changes about the way you see yourself and others.
My book 'Healthy Shouldn't Be This Hard': https://www.amazon.co.uk/Healthy-Shouldnt-Be-This-Hard-ebook/dp/B0G1DHNRV5
This episode is sponsored by:
NOWATCH: The compassionate health tracker Connecting body and mind with unique stress recovery insights so you can live fully today. 👉 15% off with code LWBW15 at https://nowatch.com/
PULSETTO: Vagus nerve stimulation for stress, sleep and calm
👉 Use code SARAHANN at https://pulsetto.sjv.io/SARAHANN
More from me: The Great British Veg Out How to support your gut by eating more, not less https://sarahmacklin.substack.com/p/t…
Reset Your Health If your body feels off after stress, travel, or burnout, this is where to start! https://sarahmacklin.substack.com/s/r...
Free 5-recipe PDF for busy weeks https://open.substack.com/pub/sarahma...
Join thousands reading The Compassionate Cure → https://sarahmacklin.substack.com/
Let's be friends!
📷 Instagram https://www.instagram.com/sarahannmacklin 📹 Subscribe https://youtube.com/@livewellbewellsarah?si=UbuuWvMjAcTkELPN 
📱 TikTok https://www.tiktok.com/@livewellbewellpodcast?_r=1&_t=ZN-96iOW29jTRm