Immune

Immune tackles papers on the breadth of human B cell responses following mRNA vaccination and on the role of mitochondria and reactive oxygen species in plasma B cell maintenance.

Hosts: Vincent Racaniello, Cindy Leifer, Stephanie Langel, and Brianne Barker
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mRNA flu vaccine expands B cell breadth (Nat Immunol, 2026)
Mitochondrial ROS and plasma cells (Nat Commun, 2026)
Time stamps by Jolene Ramsey. Thanks!
Music by Tatami.
Immune logo image by Blausen Medical

Send your immunology questions and comments to immune@microbe.tv
Information on this podcast should not be construed as medical advice.

Tanya Mayadas joins Immune to talk about her road to study neutrophils and her research findings on neutrophil antigen presentation and novel neutrophil targeting therapies.


Host: Cindy Leifer
Guest: Tanya Mayadas
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Tanya recently appointed department chair and director
Neutrophils, von Willebrand factor and P-selectin (Cell, 1991)
P-selectin knockout mouse (Cell, 1993)
Neutrophils as antigen presenting cells in cancer (Nat Comm, 2021)
Neutrophils elicit broad anti-tumor immunity (Cancer Res Comm, 2026)
FcR-mediated neutrophil recruitment (Circulation, 2009)
Neutrophil classification and heterogeneity (Immunity, 2025)
Neutrophils in Lupus (Curr Op Rheumatol, 2019)
Time stamps by Jolene Ramsey. Thanks!
Music by Tatami.
Logo image by Blausen Medical

Send your immunology questions and comments to immune@microbe.tv
Information on this podcast should not be construed as medical advice.

Adam Waickman discusses the unusual reason he got into studying immunology just in humans, his important studies on Dengue virus vaccine antibodies, and the problematic phenomenon of antibody dependent enhancement.
Host: Cindy Leifer
Guest: Adam Waickman
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Links for this episode
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Waickman Lab Website
Dengue virus human infection model (Sci Trans Med, 2022)
mRNA vectored antibody against Dengue (Antiviral Res, 2025)
B cell receptor enhancement of Dengue (PLoS Path, 2024)
Dengue infection macrophage transcriptional profiles (J Virol, 2025)
Time stamps by Jolene Ramsey. Thanks!
Music by Tatami.
Logo image by Blausen Medical

Send your immunology questions and comments to immune@microbe.tv
Information on this podcast should not be construed as medical advice.

Immune reviews new research that shows a boost in T cell function after eating and the potential for the cGAS-STING pathway to be a new lupus therapeutic target.


Hosts: Vincent Racaniello, Cindy Leifer, Stephanie Langel, and Brianne Barker
Subscribe (free): Apple Podcasts, RSS, email
Become a patron of Immune!
Links for this episode
MicrobeTV Discord Server
T cell immunity boosted after eating (Nature, 2026)
Inhibiting autoimmunity through TLR7-cGAS (Nat Comm, 2026)
Time stamps by Jolene Ramsey. Thanks!
Music by Tatami.
Immune logo image by Blausen Medical

Send your immunology questions and comments to immune@microbe.tv
Information on this podcast should not be construed as medical advice.

Stacy Horner discusses her work on innate detection of viruses, viral countermeasures, and the role of m(6)A RNA modifications in regulating antiviral immunity.
Host: Cindy Leifer
Guest: Stacy Horner

Subscribe (free): Apple Podcasts, RSS, email
Become a patron of Immune!
Links for this episode
MicrobeTV Discord Server
Hepatitis virus proteases block host response (J Virol, 2012)
Host RNA binds to MAVS (Science, 2024)
m6A modifications modify innate response to viruses (Cell Chem Biol, 2024)
UFMylation coordinates MAVS assembly for antiviral responses (bioRxiv, 2025)
Time stamps by Jolene Ramsey. Thanks!
Music by Tatami.
Logo image by Blausen Medical

Send your immunology questions and comments to immune@microbe.tv
Information on this podcast should not be construed as medical advice.