Genetics in Your World

In this episode of Genetics in Your World, GSA Early Career Scientists Multimedia Subcommittee member Racheal Asaolu has a conversation with Dr. Randall J. Roper of the School of Science at Indiana University. They discuss Roper's work. Read his paper titled, "Genetic analysis of triplicated genes affecting sex-specific skeletal deficits in Down syndrome model mice," published in the May 2026 issue of G3: Genes|Genomes|Genetics: https://doi.org/10.1093/g3journal/jkag056.

Music: Loopster Kevin MacLeod (incompetech.com). Licensed under Creative Commons: By Attribution 3.0 License, http://creativecommons.org/licenses/by/3.0/

Thank you to the Multimedia Subcommittee, particularly the production team for this episode: Racheal Asaolu, interviewer; Shruti Shastry, Audio Quality Control Coordinator; Laetitia Chauve and Anindya Ganguly, researchers.

#Trisomy21 #SkeletalDeficits #SexDifferences #MicroComputedTomography
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In this episode of Genetics in Your World, GSA Early Career Scientists Multimedia Subcommittee member Luke Arnce interviews Caitlin Peaslee of the Center for Embryonic Cell and Gene Therapy at Oregon Health and Science University about her research. Read her paper titled, "Mapping whole-organism genetic comorbidities across model species using unified ontologies," published in the April 2026 issue of GENETICS: https://doi.org/10.1093/genetics/iyag038

This study developed a cross-species computational framework, CoMo DBM, to analyze 204 mouse genes that caused non-obstructive azoospermia and mapped their phenotype associations across human, zebrafish, fruit fly, and roundworm databases.

Music: Loopster Kevin MacLeod (incompetech.com). Licensed under Creative Commons: By Attribution 3.0 License, http://creativecommons.org/licenses/by/3.0/

#GeneEditing #cancer #GeneOntology
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In this episode of Genetics in Your World, GSA Early Career Scientist Multimedia Subcommittee advisor Sarah Renee Phillips interviews Srishti Patil of the German Cancer Research Center and Dr. Robert Noble of City St. George's, University of London about their research. Read their paper titled, “Preventing evolutionary rescue in cancer using two-strike therapy,” published in the February 2026 issue of GENETICS: https://doi.org/10.1093/genetics/iyaf255.

Music: Loopster Kevin MacLeod (incompetech.com). Licensed under Creative Commons: By Attribution 3.0 License, http://creativecommons.org/licenses/by/3.0/

#evolution #cancer #GeneticRescue #variation #selection #mutation
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In this episode of Genetics in Your World, GSA Early Career Scientist Multimedia Subcommittee member Debraj Manna interviews Dr. Matt Rockman of New York University about inbreeding depression in Caenorhabditis elegans. Read Dr. Rockman's paper titled, “Variation in inbreeding depression within and among Caenorhabditis species,” published in the December 2025 issue of G3: Genes|Genomes|Genetics: https://doi.org/10.1093/g3journal/jkaf200.

Special thanks to the Production Team for this episode, ECS Multimedia Subcommittee members Debraj Manna, interviewer; Sara Shahba, researcher; and Laetitia Chauve, Audio Quality Control Coordinator.

Music: Loopster Kevin MacLeod (incompetech.com). Licensed under Creative Commons: By Attribution 3.0 License, http://creativecommons.org/licenses/by/3.0/

#genetics #Celegans #caenorhabditis #InbreedingDepression
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In this episode of Genetics in Your World, GSA Early Career Scientist Multimedia Subcommittee co-chair Sarah Renee Phillips interviews Dr. Shraddha Lall of Harvard University about the evolution of variation in behavior in Drosophila. Read Dr. Lall’s paper titled, “Family-based selection: An efficient method for increasing phenotypic variability,” published in the October 2025 issue of G3: Genes|Genomes|Genetics: https://doi.org/10.1093/g3journal/jkaf165.

Music: Loopster Kevin MacLeod (incompetech.com). Licensed under Creative Commons: By Attribution 3.0 License, http://creativecommons.org/licenses/by/3.0/

#genetics #evolution #Drosophila #behavior #variation #selection
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