Genetics in Your World

• The Evolutionary Price of Family Ties in Caenorhabditis — A Conversation with Dr. Matt Rockman

  In this episode of Genetics in Your World, GSA Early Career Scientist Multimedia Subcommittee member Debraj Manna interviews Dr. Matt Rockman of New York University about inbreeding depression in Caenorhabditis elegans. Read Dr. Rockman's paper titled, “Variation in inbreeding depression within and among Caenorhabditis species,” published in the December 2025 issue of G3: Genes|Genomes|Genetics: https://doi.org/10.1093/g3journal/jkaf200. Special thanks to the Production Team for this episode, ECS Multimedia Subcommittee members Debraj Manna, interviewer; Sara Shahba, researcher; and Laetitia Chauve, Audio Quality Control Coordinator.Music: Loopster Kevin MacLeod (incompetech.com). Licensed under Creative Commons: By Attribution 3.0 License, http://creativecommons.org/licenses/by/3.0/#genetics #Celegans #caenorhabditis #InbreedingDepression Hosted on Acast. See acast.com/privacy for more information.

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• Variation Reconsidered: Selection Schemes for Phenotypic Variability Beyond Trait Means — A Conversation with Dr. Shraddha Lall

  In this episode of Genetics in Your World, GSA Early Career Scientist Multimedia Subcommittee co-chair Sarah Renee Phillips interviews Dr. Shraddha Lall of Harvard University about the evolution of variation in behavior in Drosophila. Read Dr. Lall’s paper titled, “Family-based selection: An efficient method for increasing phenotypic variability,” published in the October 2025 issue of G3: Genes|Genomes|Genetics: https://doi.org/10.1093/g3journal/jkaf165. Music: Loopster Kevin MacLeod (incompetech.com). Licensed under Creative Commons: By Attribution 3.0 License, http://creativecommons.org/licenses/by/3.0/#genetics #evolution #Drosophila #behavior #variation #selection Hosted on Acast. See acast.com/privacy for more information.

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• Age Is Just A Number: Mapping Longevity in Diversity Outbred Mice – A Conversation with Dr. Gary Churchill

  In this episode of Genetics in Your World, GSA Early Career Scientist Multimedia Subcommittee member Faye Romero interviews Dr. Gary Churchill of the Jackson Laboratory about longevity-associated loci in diversity outbred mice. Read Dr. Churchill’s paper titled, “Analysis of lifespan across diversity outbred mouse studies identifies multiple longevity-associated loci,” published in the August 2025 issue of G3: Genes|Genomes|Genetics: https://doi.org/10.1093/genetics/iyaf081Music: Loopster Kevin MacLeod (incompetech.com). Licensed under Creative Commons: By Attribution 3.0 License, http://creativecommons.org/licenses/by/3.0/ Hosted on Acast. See acast.com/privacy for more information.

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• Breaking New Ground in Telomeric Repeat Discovery – A Conversation with Dr. George Chung

  In this installment of Genetics in Your World, GSA Early Career Scientist Multimedia Subcommittee member Laetitia Chauve interviews Dr. George Chung, a Postdoctoral Research Scientist in Dr. Kristin Gunsalus’s lab group at New York University’s Department of Biology, about a new algorithm he has developed to identify telomeres from long reads sequencing datasets. Read Dr. Chung's paper titled, “TeloSearchLR: an algorithm to detect novel telomere repeat motifs using long sequencing reads,” published in the June 2025 issue of G3: Genes|Genomes|Genetics: https://doi.org/10.1093/g3journal/jkaf062Music: Loopster Kevin MacLeod (incompetech.com). Licensed under Creative Commons: By Attribution 3.0 License, http://creativecommons.org/licenses/by/3.0/ Podcast Notes:Thank you to the GSA Early Career Scientist Multimedia Subcommittee, in particular the production team who worked on this episode: Faye Romero, Sarah Renee Phillips, Laetitia Chauve.#telomeres, #telomere repeat motif, #long-read sequencing, #nematodes Hosted on Acast. See acast.com/privacy for more information.

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• Functions of Blm Helicase N-terminal IDR — A Conversation with Dr. Evan B. Dewey

  In this episode of Genetics in Your World, GSA Early Career Scientist Multimedia Subcommittee member Allie Hutchings interviews Dr. Evan Dewey of Winthrop University about the functions of Blm helicase N-terminal IDR. Read Dr. Dewey's paper titled, “Functions of the Bloom syndrome helicase N-terminal intrinsically disordered region,” published in the March 2025 issue of GENETICS: https://doi.org/10.1093/genetics/iyaf005. Music: Loopster Kevin MacLeod (incompetech.com). Licensed under Creative Commons: By Attribution 3.0 License, http://creativecommons.org/licenses/by/3.0/ Podcast Notes:Bloom syndrome helicase (Blm) has important roles in maintaining genome stability. About half the protein is predicted to be intrinsically disordered (IDR), and its functions are poorly understood. The authors of this study identified regions that are locally conserved in closely related Drosophila species, then deleted these and assayed various functions. They find that each region is required for a subset of Blm functions. The authors’ modeling suggests these regions adopt structure in complex with Top2alpha and the results provide novel insights into Blm IDR functions. Dr. Evan Dewey would like to acknowledge the following colleagues: Colleen C. Bereda, Dr. Jeff Sekelsky, Dr. Christopher A Johnston, Denise Soroka, Dr. Mitch McVey, Carolyn Turcotte, Dr. Nila Pazhayam, Mohamed A. Nasr, Priscila Santa Rosa, Susan McMahan, Dr. Robert J. Duronio, Dr. Gregory Matera, Dr. Dan McKay, and Dr. Richard Cripps.Thank you to the GSA Early Career Scientist Multimedia Subcommittee, in particular the production team who worked on this episode: Allie Hutchings, Interviewer; Sarah Shahba and Laetitia Chauve, Researchers. Hosted on Acast. See acast.com/privacy for more information.

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