In this episode of The SHEA Podcast, Dr. Katie Chiotos (Children’s Hospital of Philadelphia) and Dr. Trevor Van Schooneveld (University of Nebraska Medical Center) discuss the stewardship of metagenomic sequencing (mNGS) in infectious disease care. They explore how to make results clinically actionable, avoid overuse or misinterpretation, and integrate mNGS into stewardship and infection prevention programs. The conversation also looks ahead to the future of mNGS and the role stewardship leaders will play in guiding its responsible use.
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24:55
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24:55
Ronald McDonald House: Measles Case Study
This episode of The SHEA Podcast was created with the SHEA Pediatric Epidemiologists and Antibiotic Stewards (PEAS) group specifically for Ronald McDonald House, but the principals would apply to any resident care facility.
As of June 2025, the world is experiencing a significant resurgence of measles. The US has documented 1,319 cases across 40 jurisdictions, marking the largest outbreak since 2020. In Europe, there were 12,694 confirmed cases over the last 12 months of reporting – the highest since 1997. Southeast Asia is also heavily affected and, Australia faces its worst outbreak since 2019. Canada has over 3,977 cases reported nationwide – the highest number since the disease was declared to be eliminated in 1998.
Together, Matthew Chater, CEO of the Ronald McDonald House in Southwestern Ontario, and Dr. Ayelet Rosenthal from Lurie Children’s Hospital of Chicago representing SHEA’s PEAS group, walk through a case study on what to do if someone infected with measles visited or stayed in a Ronald McDonald House.
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9:56
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9:56
ACIP and What Comes Next
SHEA President Dr. David Weber talks with Dr. Preeti Mehrotra and Dr. Marci Drees about their experiences as SHEA liaisons to the Advisory Committee on Immunization Practices (ACIP). They discuss reviewing vaccine data, lessons from COVID, and what the future holds for vaccines and public health.
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30:21
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30:21
Current Influences on Antimicrobial Cost
Host Dr. Jonathan Ryder speaks with Dr. Jamie Wagner and Dr. Sheetal Kandiah about the macro- and micro-influences driving antimicrobial costs. They explore how the ACA, pharmacy benefit managers, formulary restrictions, and socioeconomic disparities shape access and prescribing patterns. The discussion highlights real-world challenges for stewardship programs and practical steps to improve affordability and equity in antimicrobial use, with a look ahead at future reforms.
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21:42
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Exploration of outpatient stewardship practices and strategies for effective implementation
In this episode of the SHEA Podcast, host Dr. Jonathan Ryder, Assistant Professor in the Division of Infectious Diseases at the University of Nebraska Medical Center, speaks with Dr. Milner Staub, Assistant Professor of Medicine in the Division of Infectious Diseases at Vanderbilt University Medical Center. Their conversation explores practical, high-impact strategies for improving antimicrobial stewardship in outpatient and ambulatory care settings. With the majority of antibiotic prescribing occurring outside of hospitals, outpatient stewardship is a critical area for reducing unnecessary antibiotic use and improving patient outcomes.
Dr. Staub shares insights into her work and research, which focus on helping providers and patients optimize antibiotic prescribing in ambulatory settings. She highlights stewardship interventions that are relatively easy to implement but offer strong returns on investment. A significant part of the discussion centers around the persistent impact of penicillin allergy labels and how outpatient settings can better address this issue. Dr. Staub also discusses antibiotic overuse for acute uncomplicated bronchitis (AUB), offering recommendations for interventions to reduce inappropriate prescribing. The episode concludes with a look ahead at where more research is needed to test assumptions and develop new stewardship strategies.
Listeners are encouraged to explore SHEA’s free CDC-supported Penicillin Allergy Delabeling Course for more information. Thank you for tuning in to the SHEA Podcast.
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