Lithium May Have A Role In Causing—And Treating—Alzheimer’s
The mechanisms behind Alzheimer’s disease have eluded scientists for decades. But a new breakthrough points to lithium as a possible explanation—not only does it occur naturally in the brain, but a deficiency causes dementia in mice. This research is one of thousands of projects that have lost funding due to President Trump’s cuts to the National Institutes of Health (NIH). Host Ira Flatow speaks with Alzheimer’s researcher Bruce Yankner about this new finding, and then to epidemiologist Katelyn Jetelina and immunologist Elisabeth Marnik about the country’s “quiet engine of science,” the NIH.Guests: Dr. Bruce Yankner is professor of genetics and neurology at Harvard Medical School in Boston, Massachusetts.Dr. Katelyn Jetelina, epidemiologist and author of the Your Local Epidemiologist newsletter. She’s based in San Diego.Dr. Elisabeth Marnik is an immunologist and Director of Science Education & Outreach at the MDI Biological Laboratory in Bar Harbor, Maine.Transcripts for each episode are available within 1-3 days at sciencefriday.com.
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Are Cold Plunges Actually Good For You?
If social media and certain influential podcast hosts are to be believed, cold plunges can do everything from boosting your immune system to reducing inflammation to acting as an antidote for depression. But what does the science say? Joining Host Flora Lichtman to throw at least a few drops of cold water on this science of plunging is biologist François Haman, who studies human performance and cold exposure.And, with the help of the HBO show “Last Week Tonight,” a minor league baseball team in Pennsylvania rebranded themselves the Erie Moon Mammoths. That comes just a few months after the Utah NHL franchise renamed itself the Utah Mammoth as a nod to that state’s paleontological past. So, why are mammoths back? And do they really have what it takes to be a successful team mascot? Paleontologist Advait Jukar joins Host Flora Lichtman to weigh in.Guests: Dr. François Haman is a biologist at the University of Ottawa who studies how the human body responds to extreme environments.Dr. Advait Jukar is the assistant Curator of Vertebrate Paleontology at the Florida Museum of Natural History.Transcripts for each episode are available within 1-3 days at sciencefriday.com.
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A Nagasaki Survivor And Physician Recounts His Life's Work
Dr. Masao Tomonaga was only 2 years old when the United States bombed his home city of Nagasaki. He survived, and grew up to become a physician for other survivors, known as hibakusha. He also studied hematology, and his research on leukemia and myelodysplastic syndromes was foundational for understanding how radiation affects the body. On the 80th anniversary of the bombings of Hiroshima and Nagasaki, he speaks with Host Ira Flatow about his life’s work, how hibakusha lived with the medical consequences of the bombs, and his message to the world.Guest: Dr. Masao Tomonaga is a survivor of the atomic bombing of Nagasaki and director emeritus of the Japanese Red Cross Nagasaki Atomic Bomb Hospital.Transcripts for each episode are available within 1-3 days at sciencefriday.com.
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65 Genomes Expand Our Picture Of Human Genetics
The first complete draft of the human genome was published back in 2003. Since then, researchers have worked both to improve the accuracy of human genetic data, and to expand its diversity, looking at the genetics of people from many different backgrounds. Three genetics experts join Host Ira Flatow to talk about a recent close examination of the genomes of 65 individuals from around the world, and how it may help researchers get a better understanding of genomic functioning and diversity.Guests:Dr. Christine Beck is an associate professor of genetics and genome sciences in the University of Connecticut Health Center and the Jackson Laboratory.Dr. Glennis Logsdon is an assistant professor of genetics and a core member of the Epigenetics Institute at the University of Pennsylvania.Dr. Adam Philippy is a Senior Investigator in the Center for Genomics and Data Science Research at the National Human Genome Research Institute at the NIH.Transcripts for each episode are available within 1-3 days at sciencefriday.com.
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How The Moon Transformed Life On Earth
For almost their entire 4.5 billion-year existence, Earth and its moon have been galactic neighbors. And the moon isn’t just Earth’s tiny sidekick—their relationship is more like that of siblings, and they’re even cut from similar cosmic cloth.Without the moon, Earth and its inhabitants wouldn’t be what they are today: The climate would be more extreme, lunar tides wouldn’t have given rise to life on Earth, biological rhythms would be off-beat, and even timekeeping and religion would have evolved differently. The new book Our Moon: How Earth’s Celestial Companion Transformed The Planet, Guided Evolution, And Made Us Who We Are explores how our existence is tied to the moon’s.Ira Flatow and guest host Sophie Bushwick chat with journalist and author Rebecca Boyle about how the moon came to be, how it transformed life on Earth, and how our relationship with it is changing.Guest: Rebecca Boyle is a journalist and author of Our Moon: How Earth’s Celestial Companion Transformed The Planet, Guided Evolution, And Made Us Who We Are. She’s based in Colorado Springs, Colorado.Transcript available at sciencefriday.com.
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Covering the outer reaches of space to the tiniest microbes in our bodies, Science Friday is the source for entertaining and educational stories about science, technology, and other cool stuff.
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