Investment Climate

Episode 80: Verley Food: Hélène Briand on closing a $38M Series A without a bridge round and executing on time 

In this episode, I sit down with Hélène Briand, Co-founder and Chief Innovation & Commercial Officer at Verley Food, a French precision fermentation company that recently made headlines by closing a massive $38M Series A led by Alvin. Hélène reveals the disciplined, milestone-obsessed playbook that allowed them to go from Seed to Series A without needing a bridge round. We discuss how she proved commercial traction before having a product to sell by putting prospective customers directly on the phone with investors, why they chose to scale up with a North American CDMO rather than building their own CapEx-heavy facility, and how they secured a crucial "No Questions" letter from the FDA in record time. 
🎧 Listen to the full episode to hear why Hélène hired dedicated Project Managers to keep scientists on schedule and why focus is the ultimate fundraising hack.

Key Facts Verley Food:
Goal: To develop the next generation of functionalized whey protein (BLG) for the food industry using precision fermentation.
Milestone: Raised a $38M Series A (including significant non-dilutive backing from Bpifrance) and secured a "No Questions" letter from the FDA.

Alex’s Top Findings: 
The Power of Hitting Milestones (No Bridge Required). The FoodTech industry is notorious for delayed timelines and endless bridge rounds. Verley Food stands out because they actually delivered on the exact scientific and regulatory milestones they promised their Seed investors. Hélène attributes this to intense focus (refusing to expand beyond BLG protein) and the crucial decision to hire dedicated, non-lab-working Project Managers whose sole job is to keep the scientific team executing on schedule. "We eat on time and we have been overachieving it. And this has made the difference... We hired two project managers dedicated to execution and project management... They're not working in the lab. They're just here to manage the milestone and building the mitigation plan."
Proving Market Traction Pre-Commercialization. How do you prove traction when you don't have volume to sell? Verley Food didn't rely on theoretical TAM charts. They built an in-house applications team to solve specific pain points for FMCGs (like creating highly stable, high-protein acidic beverage shots). When it came time to fundraise, Hélène put those prospective customers directly on the phone with the VCs to vouch for the immediate market need. "We also are lucky to have good relationships with [our customers] to be able to discuss directly with our investors. So it was first of all allowing investors to touch the credibility as well on the market so they had direct access... They get on call with investors directly and we are not involved."
The Strategic CDMO Choice (And Why North America). Rather than burning capital building their own facility in France, Verley opted to scale through a Contract Development and Manufacturing Organization (CDMO) in North America. Hélène explains that finding a partner with the exact downstream filtration equipment and the "agility" to handle a startup's pace was more important than simply chasing the cheapest labor costs in Asia, especially since they are targeting a premium, high-margin functional ingredient market. "I realized how hard is it when you are in your company to handle your R&D... and on top of it manage with industrial equipment... We are leveraging CMO as much as we can until we fully de-risk the technology at industrial scale... You can make two times trying CMO all around the world. Yes, it's about price, but it is not our first criteria."

Episode 79: Arla Foods: Gilai Nachmann on Open Innovation, the AI Nutrition Threat, and How to Pilot with a €15B Dairy Giant 
In this episode, I sit down with Gilai Nachmann, Senior Project Manager of Open Innovation & Partnerships at Arla Foods, the largest dairy cooperative in Europe with €15 billion in annual revenue. Gilai breaks down Arla’s aggressive new mandate: sourcing 30% of all innovation ideas externally by 2030. He shares the exact playbook for startups looking to partner with Arla, detailing the specific problem statements they are actively funding pilots for—including sugar reduction, alternative cocoa, and navigating impending CO2 taxes. Gilai also reveals Arla's strategic fear of AI-driven personalized nutrition apps cutting FMCG brands out of the consumer relationship, and how startups can help them stay relevant in a digital-first food future. 
🎧 Listen to the full episode to hear exactly how much sample volume you need to trigger a paid pilot with Arla and why pitching them precision fermentation dairy is a non-starter.
Key Facts Arla Foods Open Innovation:
Goal: To execute an Open Innovation strategy where 30% of all new product ideas come from external sources (startups, SMEs) by 2030.
Milestone: Integrated the Open Innovation team with an internal accelerator to drastically speed up the pilot and LOI process for external startups, reducing corporate bottlenecking.

Alex’s Top Findings:
The "Goldilocks" Timing for Novel Ingredients (2 Years Out). Startups often struggle with when to approach a massive FMCG corporate. Gilai is highly specific: if you are 4-5 years away from commercialization, it is too early. However, if you are exactly two years away from EFSA (European Food Safety Authority) regulatory approval and can produce 20-50 kilos for a pilot plant test, that is the perfect time to engage Arla so they can prepare to launch alongside your approval. "If you're two years away from EFSA, I'd say that's the perfect time to engage because we want to be first runners in the area... we can all launch together when you're ready... They need to have sufficient quantity for us to pilot it... at least 20 to 50 kilos."
The Strategic Threat of AI-Driven Nutrition. Arla isn't just looking for physical ingredients; they are actively scouting digital solutions. Gilai highlights a major corporate fear: if AI agents (like ChatGPT integrated with Instacart or HelloFresh) begin dictating personalized meal plans, legacy food brands could become invisible commodities. Arla wants to partner with digital platforms to ensure their products are the recommended health solutions inside these closed AI ecosystems. "If the AI picks your food for you, what is the position of a big FMCG company in this world?... Maybe in a future where AI selects food products for you, brands don't exist. And how do we stay relevant in that future?... We don't want to build these engines... but we want to be the health partner."
Don't Pitch Precision Fermentation Dairy to a Farmer Co-op. It is critical to know your audience. While Arla is actively seeking solutions for sugar reduction and alternative cocoa, Gilai warns startups against pitching precision-fermented dairy proteins (like synthetic whey or casein). Because Arla is fundamentally a cooperative owned by dairy farmers, their mandate is to support cow-based agriculture, not replace it. "Arla is a farmer-owned cooperative. And our opinion is we're not going to look into precision fermentation as a core area for our business. We're going to focus on building our farmers' capabilities... It's not something we're going to invest in doing pilots on."

Episode 78: Ora Biotics: Jens Eklöf & Ida Krogh Sjöholm on winning Pre-Seed funding with the "Low Inclusion" fiber thesis 
In this episode, I sit down with Jens Eklöf (CEO/CTO) and Ida Krogh Sjöholm (Commercial Officer), the co-founders of Ora Biotics, a Danish startup developing the next generation of precision prebiotics. They share the tactical playbook of how they cold-called their way to a €300k pre-seed round led by Rockstart and Delphinus Venture Capital, specifically designed to fund their critical €300k US-based human clinical trial. We discuss why they pair a commercial co-founder with a technical lead from day one, how they utilized €60k in Danish government grants to survive their first year, and the exact science of why "low inclusion" fibers bypass the heavy CapEx traps that destroy other ingredient startups. 
🎧 Listen to the full episode to hear how they navigated the delicate "founder spouse" conversation regarding runway and salary expectations.

Key Facts Ora Biotics:
Goal: To produce a highly targeted, precision prebiotic fiber for metabolic health that does not cause bloating and remains 100% stable in challenging applications like acidic beverages and gummies.
Milestone: Raised a ~€300k pre-seed round (post-money cap below €2M) from Rockstart and Delphinus Venture Capital.

Alex’s Top Findings: 
The "Low Inclusion" Margin Moat. The fundamental problem with most fiber startups is that they require massive doses to be effective, which forces brands to alter recipes and forces the startup to build massive, CapEx-heavy production facilities to hit volume targets. Ora Biotics solves this by targeting specific gut bacteria, meaning their fiber requires a very low dose to be effective. This "low inclusion rate" means they can command high margins while relying entirely on asset-light Contract Manufacturers (CDMOs). "If you have lower inclusion, it's also easier to make it a drop-in solution to whatever product you just happen to have... The dose is certainly our key to get really nice margins already from the beginning. We are producing with contract manufacturers, right? We are not building a big optimized production line ourselves."
De-Risking with the "Gold Standard" Clinical Trial. While fiber can be sold legally as a food ingredient without a clinical trial, major FMCG brands will not risk their reputation (or lawsuits, a la Olipop) on unsubstantiated health claims. Orbiotics specifically raised their €300k round to fund a randomized, placebo-controlled human study in the US. This data is the exact milestone investors demanded to unlock the next funding round. "If you want to say anything about the health benefits in almost all markets in the world, you need to substantiate that... if you are a big brand and you want to know and you want the integrity to know that the ingredient you put in there gives the benefits... you want a human study. And that's also what we want to go for."
The Power of the Commercial Co-Founder at Pre-Seed. Many deep-tech startups fail because they are led by purely technical founders who wait years to speak to customers. Ora Biotics brought Ida (Commercial Officer) on board at the very beginning. Her ability to define the B2B strategy, handle investor storytelling, and secure Letters of Intent (LOIs) for food-grade sample testing before the product was even finalized was critical to winning their pre-seed funding. "I worked more on the storytelling and the market positioning and all of that, which is my background, right? I have a commercial background, I'm not a scientist... We have a few companies now who have said that they've signed the LOAs. They want to test it in their applications. So I think that is an opener."

Episode 77: Delphinus Venture Capital: Mathias Brink Lorenz on the Evergreen Advantage and the "Low Inclusion, High Margin" thesis 

In this episode, I sit down with Mathias Brink Lorenz, CEO and Managing Partner of Delphinus Venture Capital, a newly formed €80M evergreen fund backed exclusively by four major Danish corporates and a university endowment. Mathias pulls back the curtain on the perverse incentives of the traditional "10+2" VC model, explaining how the pressure to generate management fees often forces GPs into bad deals and inflated valuations. He breaks down why Delphinus operates as an evergreen structure focused solely on long-term Net IRR and why they are hyper-focused on the Danish ecosystem. Finally, Mathias delivers a masterclass on FoodTech unit economics, explaining why commodity alternatives (like cocoa or bulk protein) struggle, and why the real venture returns lie in "low inclusion, high margin" ingredients like enzymes and complex savory flavors.

Key Facts Delphinus Venture Capital:
Goal: To deploy an €80M evergreen fund into Danish research-focused startups (Pre-Seed to Series B) across AgriFood, Bioeconomy, MedTech, and Dual-Use tech.
Milestone: Successfully launched the fund with an unusual and highly aligned LP base of three major Danish corporates (Norlys, Heartland, Salling Group) and Aarhus University Research Foundation (AUFF).

Alex’s Top Findings: 
The Flaw in the Traditional VC Model. Mathias offers a candid critique of the standard 10-year venture capital structure. He argues that traditional VCs are incentivized to optimize for management fees and short-term paper markups to raise their next fund, rather than focusing on the long-term health of the startup. Delphinus uses an evergreen structure with a lower management fee, tying GP compensation almost entirely to carry, ensuring alignment with the founders' actual path to profitability rather than artificial valuation bumps. "A traditional VC is under pressure to invest at a certain pace no matter if the deal is good or not... What is it you are solving for at seed stage? A high evaluation... just to get to the next fund. So all of those behaviors inherent in the ecosystem of VCs, we're trying not to go to."
The "Picks and Shovels" Strategy for FoodTech. Startups building massive, capital-intensive indoor farms or attempting to replace bulk commodities often suffer from terrible gross margins. Mathias advises focusing on the technology that enables the industry—the "picks and shovels." He looks for B2B solutions and enabling technologies that offer high-margin support to the broader AgriFood ecosystem. "Often it's better to put on the picks and shovels approach... those would be the great sort of VC bets rather than the individual miner going into the mountain and maybe striking silver or gold... And I think I see the same in agri-food tech... betting on the high-tech solutions, high-margin supporting technologies."
The "Low Inclusion, High Margin" Ingredient Thesis. Why did Delphinus invest in Reduced (savory flavors) and Orbiotics (prebiotics)? Because they follow the enzyme playbook. When your ingredient makes up only a tiny fraction of the end product's total volume (low inclusion rate) but is critical to the product's function, flavor, or label (high value), you can command massive gross margins without significantly impacting the FMCG's overall unit cost. "If you sell a loaf of bread, the actual cost assigned to the enzyme is minuscule. What really matters for your unit cost is the flour... So if the color [or flavor] makes all the difference for how the yogurt is perceived... you can charge a premium. It's really about how much of the total product cost do you constitute with your own ingredient."

Episode 76: Proba: Sijbrand Tieleman on raising an Extension Round and dominating a hyper-niche market 
In this episode, I sit down with Sijbrand Tieleman, Co-founder and CEO of Proba, an Amsterdam-based startup tackling the massive footprint of fertilizer emissions. Sijbrand walks us through his recent €1.25M ($1.5M USD) extension round, which was led by existing investor Future Food Fund. We discuss the strategic decision to raise from the current cap table rather than burning time chasing new investors, the reality of setting achievable milestones, and why agriculture startups cannot be measured by traditional SaaS ARR metrics. Most importantly, Sijbrand delivers a masterclass on finding a competitive moat by becoming the absolute world leader in a highly specific, hyper-niche use case before expanding into larger markets. 
🎧 Listen to the full episode to hear how Sijbrand navigated the delicate valuation negotiations with his existing investors to secure 18-24 months of runway.
Key Facts Proba:
Goal: To help the agri-food supply chain quantify and reduce greenhouse gas emissions specifically related to fertilizer use.
Milestone: Recently closed a €1.25M extension round, primarily funded by their existing investors, to focus entirely on business execution without the distraction of a protracted fundraising roadshow.
Alex’s Top Findings: 
The Power of the Hyper-Niche. Startups often fail by trying to solve too many problems across too many industries. Proba initially explored steel and cement before pivoting entirely to fertilizer emissions. Sijbrand explains that by picking a "vertical within a vertical," Proba created a monopoly. They didn't just target agriculture; they targeted the specific emissions effect of nitrification inhibitors used alongside urea fertilizer for coffee grown in the Minas Gerais region of Brazil. "The more opportunity you give yourself to become successful, that I think is kind of a lesson... just make it super small and then extend from there... You want to position yourself in a way that there's no competition. If somebody wants to solve the problem, they more or less need to come to you."
The "Insider" Extension Round. Instead of spending 8 months pitching 100 new VCs, Proba chose to raise an extension round directly from their current investors. Sijbrand reveals that they began discussing the need for this follow-on capital just two months after closing the previous round. By maintaining transparent communication and setting realistic milestones, they secured the cash needed to focus on the business rather than the roadshow. "We kind of took a bit of an implicit decision to say... we can go out there to the capital market and basically spend a lot of time finding a new investor without guarantee on success, or we spent a bit less time together with the existing investors and basically have more time to spend in the actual business."
Agriculture SaaS is Not Silicon Valley SaaS. Sijbrand highlights a critical disconnect between generalist VCs and AgTech startups. Generalist funds demand rapid Month-over-Month Monthly Recurring Revenue (MRR) growth. However, agriculture operates on physical, annual growing seasons. Proba partnered with specialized investors (Future Food Fund) who understand that growth in this sector is a compounding, season-by-season process, not an overnight software rocket ship. "Building a business in agriculture has a bit of a different speed... things need to grow in a physical world and they grow in one growing season... The normal SaaS investors who are used to [rapid] ARR levels are not interested yet.”