The MCG Pediatric Podcast

• Neonatal CMV and Universal Screening

  Did you know that congenital cytomegalovirus (cCMV) is the most common congenital viral infection in newborns and a leading cause of non-genetic hearing loss? Despite its prevalence, awareness and screening for cCMV remain inconsistent across healthcare systems. In this episode, we dive into the critical importance of cCMV screening, early diagnosis, and intervention. Join our expert guests Dr. Ingrid Camelo and Dr. John Noel as they discuss: The impact of cCMV on neonatal and long-term health outcomes Best practices for screening and diagnostic methods The role of early intervention, including antiviral therapy How advocacy efforts are shaping the future of universal screening policies Tune in to stay informed on how pediatricians and healthcare providers can play a vital role in improving outcomes for infants affected by cCMV. Special thanks to Dr. James Grubbs for peer reviewing this episode. CME Credit (requires free sign up): Link Coming Soon! References:  American Academy of Pediatrics. A targeted approach for congenital cytomegalovirus. Available at: https://publications.aap.org/pediatrics/article/139/2/e20162128/60211/A-Targeted-Approach-for-Congenital-Cytomegalovirus. Accessed August 13, 2024. Chiopris G, Veronese P, Cusenza F, Procaccianti M, Perrone S, Daccò V, Colombo C, Esposito S. Congenital cytomegalovirus infection: update on diagnosis and treatment. Microorganisms. 2020 Oct 1;8(10):1516. doi: 10.3390/microorganisms8101516. PMID: 33019752; PMCID: PMC7599523. Gantt S. Newborn cytomegalovirus screening: is this the new standard? Curr Opin Otolaryngol Head Neck Surg. 2023 Dec 1;31(6):382-387. doi: 10.1097/MOO.0000000000000925. Epub 2023 Oct 11. PMID: 37820202. Minnesota Department of Health. Minnesota implements universal newborn screening for cytomegalovirus. Available at: https://www.health.state.mn.us/news/pressrel/2023/ccmv020823.html. Accessed August 13, 2024. National CMV Foundation. Advocacy: universal newborn CMV screening. Available at: https://www.nationalcmv.org/about-us/advocacy#:~:text=Minnesota%20was%20the%20first%20state%20to%20enact%20universal%20newborn%20CMV%20screening. Accessed August 13, 2024. New York State Department of Health. Newborn screening for cytomegalovirus. Available at: https://www.health.ny.gov/press/releases/2023/2023-09-29_newborn_screening.htm#:~:text=ALBANY%2C%20N.Y.,all%20babies%20for%20the%20virus. Accessed August 13, 2024. UpToDate. Congenital cytomegalovirus (CMV) infection: clinical features and diagnosis. Available at: https://www.uptodate.com/contents/congenital-cytomegalovirus-ccmv-infection-clinical-features-and-diagnosis?search=cmv%20screening&source=search_result&selectedTitle=1%7E28&usage_type=default&display_rank=1#H92269684. Accessed August 13, 2024. UpToDate. Congenital cytomegalovirus (CMV) infection: management and outcome. Available at: https://www.uptodate.com/contents/congenital-cytomegalovirus-ccmv-infection-management-and-outcome?search=congenital%20cmv&source=search_result&selectedTitle=2%7E66&usage_type=default&display_rank=2. Accessed August 13, 2024. UpToDate. Ganciclovir and valganciclovir: an overview. Available at: https://www.uptodate.com/contents/ganciclovir-and-valganciclovir-an-overview?search=ganciclovir&source=search_result&selectedTitle=2%7E80&usage_type=default&display_rank=1#H6. Accessed August 13, 2024. University of Texas Medical Branch. Neonatology manual: infectious diseases. Available at: https://www.utmb.edu/pedi_ed/NeonatologyManual/InfectiousDiseases/InfectiousDiseases3.html#:~:text=may%20be%20required.-,Cytomegalovirus,Clinical%20findings. Accessed August 13, 2024. National Center for Biotechnology Information. Cytomegalovirus (CMV) infection. Available at: https://www.ncbi.nlm.nih.gov/books/NBK541003/. Accessed August 13, 2024.                                                                                                             

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  28:01
• Contraception Counseling in Adolescents

  The adolescent population is experiencing increasing pressure to take part in sexual activity. It is part of our role as pediatricians to counsel our patients appropriately & thoroughly through their sexual & reproductive health. Dr. Shreeti Kapoor, a general pediatrician, joins Pediatric Resident Dani Watson & MS3 Irielle Duncan to discuss contraception options & how to have those conversations with adolescent patients. Specifically, they will: Review the efficacy, mechanism of action, potential adverse effects, and benefits of various contraceptive options, including abstinence, barrier methods, combination hormonal contraceptives, Depo Provera, and LARCs.  Discuss how to obtain relevant medical and sexual history to help in choosing an appropriate contraceptive for an adolescent patient.  Identify potential barriers or considerations that are specific for adolescent patients when discussing contraceptives.  Discuss options for emergency contraception & their mechanisms of action.  Special thanks to Drs. Rebecca Yang & Danielle Rosema for peer reviewing this episode. CME Credit (requires free sign up):  Click Here References:  https://www.aafp.org/pubs/afp/issues/2003/0401/p1571.html https://www.cdc.gov/nchs/products/databriefs/db366.htm#:~:text=By%20age%2015%2C%2021%25%20of,had%20ever%20had%20sexual%20intercourse. https://www.plannedparenthood.org/learn/birth-control/withdrawal-pull-out-method/how-effective-is-withdrawal-method-pulling-out#:~:text=What%20we%20do%20know%20is,or%20not%20you%27re%20ovulating. https://www.acog.org/womens-health/faqs/barrier-methods-of-birth-control-spermicide-condom-sponge-diaphragm-and-cervical-cap https://www.acog.org/clinical/clinical-guidance/practice-bulletin/articles/2017/11/long-acting-reversible-contraception-implants-and-intrauterine-devices https://www.acog.org/womens-health/faqs/combined-hormonal-birth-control-pill-patch-ring https://www.acog.org/womens-health/faqs/progestin-only-hormonal-birth-control-pill-and-injection https://www.aafp.org/pubs/afp/issues/1998/0801/p522.html https://www.acog.org/womens-health/infographics/effectiveness-of-birth-control-methods      

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  24:48
• Early Language Developmental Delay

  Language delays are one of the most common concerns brought up in pediatric well visits. Dr. Jennifer Poon, a pediatric specialist in Development and Behavior, joins Dr. Sarah Straka and medical student Alisha Patel to discuss how to recognize and manage language delays. Specifically, they will: Define and understand language delay. Recognize the initial signs and symptoms of language delays. Identify and explain clinical pearls of potential etiologies of language delays. Recognize the developmental milestones for language based on age. Discuss the prevalence of language delays as well as identify the risk factors and patient demographics that have an increased susceptibility. Understand the initial diagnostic approach to the child with suspected language delay. Review the most common interventions when a child has language delay. Understand how to best discuss the prognosis for language delays and counsel the families and caregivers CME Credit (requires free sign up): https://mcg.cloud-cme.com/course/courseoverview?P=0&EID=19528 References: Karani NF, Sher J, Mophosho M. The influence of screen time on children's language development: A scoping review. S Afr J Commun Disord. 2022 Feb 9;69(1):e1-e7. doi: 10.4102/sajcd.v69i1.825. PMID: 35144436; PMCID: PMC8905397. Law, James et al. “Speech and language therapy interventions for children with primary speech and/or language disorders.” The Cochrane Database of Systematic Reviews 2017,1 CD012490. 9 Jan. 2017, doi:10.1002/14651858.CD012490 Sices, Laura, and Marilyn Augustyn. “Expressive Language Delay (‘Late Talking’) in Young Children.” Edited by Robert G Voigt and Mary Torchia, UptoDate, Wolters Kluwer, UpToDate, Inc., 25 Jan. 2022, https://www.uptodate.com/contents/expressive-language-delay-late-talking-in-young-children. Spratt, Eve G et al. “The Effects of Early Neglect on Cognitive, Language, and Behavioral Functioning in Childhood.” Psychology (Irvine, Calif.) 3,2 (2012): 175-182. doi:10.4236/psych.2012.32026 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3652241/ Sunderajan, Trisha, and Sujata V Kanhere. “Speech and language delay in children: Prevalence and risk factors.” Journal of family medicine and primary care 8,5 (2019): 1642-1646. doi:10.4103/jfmpc.jfmpc_162_19 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6559061/ Takahashi I, Obara T, Ishikuro M, et al. Screen Time at Age 1 Year and Communication and Problem-Solving Developmental Delay at 2 and 4 Years. JAMA Pediatr.Published online August 21, 2023. doi:10.1001/jamapediatrics.2023.3057 Young, Allen. and Matthew Ng. “Genetic Hearing Loss.” StatPearls, StatPearls Publishing, 17 April 2023. https://www.ncbi.nlm.nih.gov/books/NBK580517/ Zuckerman B, Khandekar A. Reach Out and Read: evidence based approach to promoting early child development. Curr Opin Pediatr. 2010 Aug;22(4):539-44. doi: 10.1097/MOP.0b013e32833a4673. PMID: 20601887.

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  24:46
• Male Neonatal Circumcision

  To Snip or Not to Snip - prepare for a “Cut” above the rest. On this episode of the MCG Pediatric Podcast, Dr. Bradley Morganstern, a Pediatric Urology physician, joins General Pediatrician Dr. Lauren Smith and Pediatric Resident Dr. My Duyen Vo to discuss the procedure of routine neonatal male circumcision, including benefits, potential complications, and contraindications. In this podcast, they will: Review the basic procedure for routine neonatal circumcision Discuss the benefits and risks associated with circumcision Depict the potential complications from circumcision that may require further intervention from urology Present the current guidelines on male circumcision from the American Academy of Pediatrics (AAP) Explore the history and cultural traditions surrounding circumcision Special thanks to Dr. Rebecca Yang and Dr. Alice Little Caldwell for peer reviewing this episode CME Credit (requires free sign up):  https://mcg.cloud-cme.com/course/courseoverview?P=0&EID=19526 References: Aggleton, Peter (2007). “Just a Snip?”: A Social History of Male Circumcision, Reproductive Health Matters, 15:29, 15-21, DOI: 10.1016/S0968-8080(07)29303-6 Blank MD, S., Brady MD, M., Buerk MD, E., Carlo MD, W., Diekema MD, D., Freedman MD, A., Maxwell MD, L., Wegner MD, S. (2012). TASK FORCE ON CIRCUMCISION. Circumcision Policy Statement. Pediatrics, 130 (3): 585-586. https://doi.org/10.1542/peds.2012-1989 Blank MD, S., Brady MD, M., Buerk MD, E., Carlo MD, W., Diekema MD, D., Freedman MD, A., Maxwell MD, L., Wegner MD, S. (2012). TASK FORCE ON CIRCUMCISION. Male Circumcision Technical Report. Pediatrics, 130 (3): e756–e785. 10.1542/peds.2012-1990 Centers for Disease Control and Prevention (CDC). (2021). Protect Your Baby from Bleeds – Talk to Your Healthcare Provider about Vitamin K [Fact Sheet]. U.S. Department of Health & Human Services. https://www.cdc.gov/ncbddd/blooddisorders/documents/vitamin-k-p.pdf Kaweblum, Y. A., Press, S., Kogan, L., et al (1984). Circumcision using the Mogen clamp. Clin Pediatr (Phila.) 23:679-82. Morris, B. J., Bailis, S. A., Wiswell, T. E. (2014). Circumcision Rates in the United States: Rising or Falling? What Effect Might the New Affirmative Pediatric Policy Statement Have? Mayo Clinic Proceedings, 89 (5): 677-686. https://doi.org/10.1016/j.mayocp.2014.01.001 Owings M, Uddin S, Williams S. (2013). Trends in circumcision for male newborns in U.S. hospitals: 1979-2010. Atlanta, Georgia: Centers for Disease Control and Prevention. http://www.cdc.gov/nchs/data/hestat/circumcision_2013/circumcision_2013.pdf Smith, L. The History of Male Infant Circumcision(Medical resident thesis).  WHO, UNAIDS (2010). Neonatal and child male circumcision: A global review. www.circlist.com/considering/neonatal_child_MC_UNAIDS.pdf

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  25:50
• Specific Learning Disorders

  Did you know that approximately 1 in 5 children experience learning and attention issues, but only a fraction of them receives an official diagnosis? In this episode of the MCG Pediatric Podcast, hosts Rishab Chawla and Dr. Jennifer Poon delve into the topic of Specific Learning Disorders (SLDs). They discuss the prevalence, diagnostic criteria, assessment methods, and treatment interventions for SLDs. The conversation aims to provide a comprehensive understanding of SLDs and highlight the importance of early intervention and support. CME Credit (requires free sign up):  https://mcg.cloud-cme.com/course/courseoverview?P=0&EID=19525 References: Barto, A. The State of Learning Disabilities: Understanding the 1 in 5. Available from: https://ldaamerica.org/lda_today/the-state-of-learning-disabilities-today/. Dominguez, O. and P. Carugno, Learning Disability, in StatPearls. 2024, StatPearls Publishing: Treasure Island (FL). About learning disorders and disabilities. Available from: https://www.childrenshospital.org/conditions/learning-disorders-and-disabilities. Learning Disabilities: Overview. Available from: https://www.nhs.uk/conditions/learning-disabilities/. Intellectual Developmental Disorder (Intellectual Disability). 2022, American Psychiatric Association. Developmental, A.S.o. and B. Pediatrics, AAP Developmental and Behavioral Pediatrics, ed. R.G. Voigt, et al.: American Academy of Pediatrics. Burns, M.K., et al., Toward a Unified Response-to-Intervention Model: Multi-Tiered Systems of Support, in Handbook of Response to Intervention: The Science and Practice of Multi-Tiered Systems of Support, S.R. Jimerson, M.K. Burns, and A.M. VanDerHeyden, Editors. 2016, Springer US: Boston, MA. p. 719-732. Health Issues & Treatments for Spina Bifida. 2023; Available from: https://www.cdc.gov/NCBDDD/spinabifida/treatment.html. Leonard, H., et al., A systematic review of the biological, social, and environmental determinants of intellectual disability in children and adolescents. Frontiers in Psychiatry, 2022. 13. Snowling, M.J., A. Gallagher, and U. Frith, Family risk of dyslexia is continuous: individual differences in the precursors of reading skill. Child Dev, 2003. 74(2): p. 358-73. Felitti, V.J., et al., Relationship of Childhood Abuse and Household Dysfunction to Many of the Leading Causes of Death in Adults: The Adverse Childhood Experiences (ACE) Study. American Journal of Preventive Medicine, 1998. 14(4): p. 245-258. Zarei, K., et al., Adverse Childhood Experiences Predict Common Neurodevelopmental and Behavioral Health Conditions among U.S. Children. Children (Basel), 2021. 8(9). CDC’s Developmental Milestones. 2023; Available from: https://www.cdc.gov/ncbddd/actearly/milestones/index.html. Lipkin, P.H., et al., Promoting Optimal Development: Identifying Infants and Young Children With Developmental Disorders Through Developmental Surveillance and Screening. Pediatrics, 2020. 145(1). IEP and 504 plans. Available from: https://www.choa.org/-/media/Files/Childrens/patients/school-program/iep-504-resource-page.pdf?la=en&hash=BF719764C11B474F8659306C061E00FD938CE5D0. Individuals with Disabilities Education Act Sec. 300.8 Child with a disability. 2018. Affects focus, attention and behavior and can make learning challenging. Available from: https://ldaamerica.org/disabilities/adhd/. Sahoo, M.K., H. Biswas, and S.K. Padhy, Psychological Co-morbidity in Children with Specific Learning Disorders. Journal of Family Medicine and Primary Care, 2015. 4(1): p. 21-25. Ee, J., B. Stenfert Kroese, and J. Rose, A systematic review of the knowledge, attitudes and perceptions of health and social care professionals towards people with learning disabilities and mental health problems. British Journal of Learning Disabilities, 2022. 50(4): p. 467-483. From the Boston Globe: "How to Support your Dyslexic Child". 2021; Available from: https://dyslexia.yale.edu/boston-globe-support-dyslexic-child/. Resources https://ldaamerica.org/resources/ American Academy of Pediatrics. https://www.healthychildren.org/English/health-issues/conditions/learning-disabilities/Pages/default.aspx

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  25:28

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