DNA Today: A Genetics Podcast

This is our seventh installment in our Mock Genetic Counseling Session Series! In this episode, genetic counselor and teratogen information specialist Sharon Voyer Lavigne and student Edith Atwerebour perform a mock genetic counseling session. The session indication is medication exposures during pregnancy, including Ozempic®, metformin, Zoloft®, and Xanax®.

This session was recorded in person, providing a more dynamic and engaging learning experience. Therefore, we highly recommend watching it on YouTube to fully immerse yourself in the interaction.

We hope this series is helpful for prospective and current genetic counseling students, as well as the general public, by demystifying the genetic counseling process. 

The Actors:
Edith Atwerebour is currently a student in the Human Genetics Program at Sarah Lawrence College training to become a genetic counselor. In this mock session, she plays Denise, a 34-year-old woman who is pregnant with her second child and seeking information about medication exposures during pregnancy. The premise of this mock case was developed as part of Atwerebour’s internship with DNA Today.

Sharon Voyer Lavigne, MS, LGC, is a licensed genetic counselor, teratogen information specialist, and Coordinator of MotherToBaby Connecticut. She has worked with MotherToBaby Connecticut for more than 28 years and also serves as its Research Coordinator. Lavigne is a Clinical Instructor in the Division of Human Genetics within the Department of Genetics and Genome Sciences at UConn Health. She teaches and trains genetic counseling students, maternal-fetal medicine fellows, OB/GYN residents, and other healthcare professionals.

Lavigne received her Bachelor of Science in Biology from Northeastern University and her Master of Science in Human Genetics/Genetic Counseling from Sarah Lawrence College. Through MotherToBaby, she helps patients and healthcare professionals understand the most current evidence about medications and other exposures during pregnancy and breastfeeding.

Mock Session Overview:

How genetic counselors establish the approximately 3% background risk for birth defects before discussing specific exposures

Why the timing, dose, frequency, and duration of a medication exposure matter

What is currently known, and still unknown, about semaglutide (Ozempic®/Wegovy®) exposure during early pregnancy

Why controlling type 2 diabetes may be more important than the medication exposure itself

The role of metformin, insulin, maternal-fetal medicine specialists, and diabetes educators during pregnancy

What research suggests about sertraline (Zoloft®) use and the risk for structural birth defects

How untreated anxiety and depression can also affect maternal and pregnancy health

Possible newborn adaptation symptoms following exposure to certain psychiatric medications

Why patients should consult their healthcare providers before reducing or discontinuing medication

How therapy, family support, and postpartum planning can complement medication management

The role of anatomy ultrasounds and fetal echocardiograms in pregnancy monitoring

How MotherToBaby helps patients and healthcare providers navigate exposures during pregnancy and breastfeeding

The central takeaway from the session is that Denise’s reported medication exposures are not expected to place the pregnancy at a significantly greater overall risk. Instead, the primary priorities are improving diabetes control, maintaining her mental health, and coordinating care among her obstetrician and other healthcare providers.

MotherToBaby Resources:
MotherToBaby provides free, evidence-based information about medications and other exposures during pregnancy and breastfeeding. Patients and healthcare providers can contact MotherToBaby by phone, text, email, or live chat.

MotherToBaby Pregnancy and Breastfeeding Fact Sheets

MotherToBaby: Semaglutide (GLP-1s like Ozempic®, Wegovy®, Rybelsus®)

MotherToBaby: Metformin (Glucophage®, Glumetza® and Fortamet®) 

MotherToBaby: Sertraline (Zoloft®)

MotherToBaby: Alprazolam (Xanax®, Niravam®, Gabazolamine-0.5®)

Previous Installments of Our Mock Genetic Counseling Session Series:
Episode #311: Cancer Session for Breast and Prostate Cancer Family History

Episode #317: Prenatal Session for Advanced Maternal Age

Episode #331: Pediatric Session for Autism

Episode #351: Cardio Session for Sudden Death of a Family Member

Episode #368: Prenatal Session for Increased Nuchal Translucency

Episode #373: Pediatric Session for an Abnormal Cystic Fibrosis Newborn Screening Result

Disclaimer:
Please note that the information provided in this mock genetic counseling session is intended strictly for educational purposes and should not be used for personal medical decision-making. Medication risks and benefits during pregnancy vary based on the individual, medication, dose, timing, and underlying medical condition.

If you have questions or concerns about your health, we encourage you to consult directly with a certified genetic counselor or another qualified healthcare provider who can provide individualized medical recommendations. If you are in the United States, you can find a genetic counselor near you by visiting FindAGeneticCounselor.com. 

Connect with DNA Today:
You never have to wait long for a new episode of DNA Today, we release episodes every Friday! In the meantime, explore our library of over 400 episodes on Apple Podcasts, Spotify, DNAToday.com, or wherever you listen to podcasts. Just search “DNA Today.”

Prefer to watch? The video version of this episode is available on our YouTube channel and DNAToday.com. Select episodes are filmed in person, including some at the iconic NBCUniversal studios.

Discover more podcasts exploring genetics, genomics, medicine, and science from our network, Gene Pool Media: The Science Podcast Network.

DNA Today is hosted and executive produced by Kira Dineen, MS, LCGC, CG(ASCP)CM. Liv Davidson is our Social Media Lead and Eric Knaus is our Digital Marketing and Automation Lead.

Genetic testing can change the course of a patient’s care, but accessing the right test is not always straightforward.

Behind the scenes, insurance coverage decisions, documentation requirements, prior authorization, denials, appeals, and cost concerns can all influence whether a patient receives timely answers.

In this episode of DNA Today, we launch a new special series sponsored by Revvity in this episode exploring the health economics of genetic testing and the real-world systems that shape access to genomic medicine.

Host Kira Dineen is joined by Dr. Madhuri Hegde, Senior Vice President and Chief Scientific Officer at Revvity, and Mackenzie Mosera Derby, a pediatric genetic counselor at UW Health. Together, they examine genetic testing access from both the diagnostic laboratory and clinical perspectives exploring why insurance coverage remains so inconsistent, what goes into a prior authorization, why genetic tests are commonly denied, and how clinicians can approach appeals and peer-to-peer reviews.

In This Episode, We Discuss

The transition from stacked laboratory procedure codes to codes for genes, panels, exomes, and genomes

How and why insurance coverage varies among payers and individual health plans

Coverage differences across hereditary cancer testing, exome sequencing, genome sequencing, reproductive testing, and population screening

How rapid and ultra-rapid genome sequencing may be covered differently from standard genome sequencing

The limited coverage available for preventive and population-based genomic testing

The coordination required among patients, clinicians, laboratories, and insurance companies

Why laboratories offering tests with similar names may differ in technology, interpretation, turnaround time, and clinical support

What documentation is typically required for a genetic testing prior authorization

How clinicians demonstrate medical necessity and clinical utility

Why professional guidelines and peer-reviewed literature can strengthen an authorization request

The role laboratories play in benefits investigations, billing assistance, financial support, and prior authorization

Why laboratories may perform testing without knowing whether they will ultimately be reimbursed

Common reasons insurance companies deny genetic testing

Why “this test will not change clinical management” can be an overly narrow interpretation of genetic testing’s value

How genetic results may inform surveillance, reproductive decisions, recurrence risks, family members, research eligibility, and patient support

The role of hospital test utilization committees

Why genetic counselors and geneticists should be represented on utilization review teams

How letters of medical necessity (LOMN) and peer-to-peer reviews may support an appeal

Why genetic counselors may be prevented from conducting peer-to-peer reviews, even when they were the ordering provider

The time clinicians spend educating insurance representatives about genetics

Why payer policies frequently lag behind genomic technology and professional recommendations

The importance of detailed clinical documentation and accurate diagnostic coding

The difference between prior authorization, insurance coverage, and guaranteed payment

How self-pay pricing and misleading “no-cost” language can create confusion

The potential devaluation of genetic testing and genetic counseling services through complementary or low cost self-pay options 

Why improving access requires collaboration among patients, clinicians, laboratories, professional organizations, healthcare systems, and payers

About The Guests 
Madhuri Hegde, PhD, FACMG, is the Senior Vice President and Chief Scientific Officer at Revvity, where she leads the company’s scientific strategy and oversees Revvity Omics’ global network of laboratories.

Dr. Hegde is a medical geneticist and an American Board of Medical Genetics and Genomics-certified diplomate in clinical molecular genetics. Her work focuses on advancing genomic technologies and expanding access to diagnostic testing for patients with rare and inherited conditions. Before joining industry, Dr. Hegde served as Executive Director of the Emory Genetics Laboratory and as a professor of human genetics and pediatrics at Emory University.

She has previously joined DNA Today to discuss whole-genome sequencing, Duchenne muscular dystrophy, and rapid genome sequencing in the neonatal intensive care unit.

Mackenzie Mosera Derby, MS, CGC, is a pediatric genetic counselor at UW Health and the University of Wisconsin–Madison Division of Genetics and Metabolism.

Her work includes pediatric and inpatient genetics, genetic testing utilization, clinical education, and improving the systems through which patients access genetic services.

Mackenzie also teaches genetic counseling students and brings experience examining how documentation, insurance authorization, utilization review, and multidisciplinary collaboration affect patient care.

Resources

American College of Medical Genetics (ACMG) Evidence-Based Clinical Practice Guidelines (EBGs)

National Society of Genetic Counselors (NSGC) Billing and Reimbursement Resources (including CPT codes) 

American Medical Association (AMA) creation of Current Procedural Terminology (CPT®) codes

Centers for Medicare & Medicaid Services (CMS), which is the U.S. federal agency that provides health coverage to more than 160 million through Medicare, Medicaid, the Children's Health Insurance Program, and the Health Insurance Marketplace. 

Health literacy paper referenced by Mackenzie sharing that only 12% of U.S. adults had “proficient” health literacy. Data was collected in 2003 and the paper was published in 2006. 

Revvity website 

 

Related DNA Today Episodes
#394 How Newborn Sequencing Could Transform Pediatric Rare Disease Care in Florida
Dr. Pradeep Bhide and Florida State Representative Adam Anderson discuss the Sunshine Genetics Act and a voluntary newborn genome-sequencing pilot program. The episode examines how earlier genomic testing could shorten the diagnostic odyssey and expand access to rare disease diagnoses for children and families.

#298 Genetic Counselors’ Role in Insurance with Stephanie Gandomi
Genetic counselor Stephanie Gandomi shares her experience working within health insurance and explores prior authorization, payer medical policies, laboratory market access, and the role genetic counselors can play in coverage decisions.

#226 NICU Whole-Genome Sequencing with Hong Li and Madhuri Hegde
Dr. Hong Li and Dr. Madhuri Hegde discuss the use of rapid whole-genome sequencing for critically ill newborns, including how faster diagnoses may affect treatment, medical management, and healthcare utilization.

#202 Duchenne Muscular Dystrophy with Ann Martin and Madhuri Hegde
Genetic counselor Ann Martin and Dr. Madhuri Hegde explore the genetics of Duchenne muscular dystrophy, available genetic testing options, and emerging treatments.

#177 Whole-Genome Sequencing with PerkinElmer Genomics (aka Revvity)
Dr. Madhuri Hegde explains whole-genome sequencing, how it compares with other genetic testing approaches, and its growing role in diagnosing rare and inherited disorders.

#180 Reproductive DNA Testing with Mitera
This episode explores reproductive genetic testing, including insurance billing, prior authorization, self-pay options, and the financial considerations patients may encounter when pursuing testing.

 

Connect with DNA Today
You never have to wait long for a new episode of DNA Today, we release episodes every Friday! In the meantime, explore our library of over 400 episodes on Apple Podcasts, Spotify, DNAToday.com, or wherever you listen to podcasts. Just search “DNA Today.”

Prefer to watch? The video version of this episode is available on our YouTube channel and DNAToday.com. Select episodes are filmed in person, including some at the iconic NBCUniversal studios.

Discover more podcasts exploring genetics, genomics, medicine, and science from our network, Gene Pool Media: The Science Podcast Network.

DNA Today is hosted and executive produced by Kira Dineen, MS, LCGC, CG(ASCP)CM. Liv Davidson is our Social Media Lead and Eric Knaus is our Digital Marketing and Automation Lead. 

Follow us at @DNATodayPodcast on all platforms including Instagram, X, BluSky, Threads, LinkedIn, Facebook, YouTube and our website, DNAToday.com. 

Questions, partnership inquiries, and guest pitches can be sent to info@DNAToday.com.

What happens when someone known for strength, stature, and intimidating roles faces a diagnosis most people do not associate with men?

 

Tyler Mane is known for playing Sabretooth in X-Men and Deadpool & Wolverine, Michael Myers in Halloween, and Ajax in Troy. Before his acting career, Tyler spent more than a decade wrestling professionally around the world, including appearances with WCW and UWF as Big Sky and Nitron. Recently, Tyler has taken on a very different role: raising awareness about male breast cancer.

 

Tyler joins host Kira Dineen to share his experience of discovering a breast lump, initially believing it was a lipoma, having his concerns dismissed, and ultimately receiving a breast cancer diagnosis. He opens up about his first instinct to keep the diagnosis private, the embarrassment he initially felt, and what motivated him to speak publicly.

Episode Discussion Topics

The breast lump that led Tyler to seek medical care

Why Tyler and his wife, Renae, initially believed the lump was a lipoma

Having his concerns dismissed and continuing to pursue answers

Tyler’s first reaction to his breast cancer diagnosis

The embarrassment and stigma surrounding male breast cancer

Why he ultimately decided to share his story publicly

Symptoms and physical changes men should pay attention to

How masculinity and “toughing it out” can delay medical care

The importance of self-advocacy and early detection

How cancer treatment differs from the physical demands of wrestling

Redefining strength during illness and recovery

Genetic counseling and germline genetic testing after a male breast cancer diagnosis

The implications of Tyler’s BRCA2+ genetic testing results for treatment and relatives including his adult children 

How Tyler’s public image affects the response to his diagnosis

Tyler and Renae’s upcoming podcast, MANE AF

 

Resources & Links

Tyler Mane’s Breast Cancer Announcement Instagram Video
@TheRealTylerMane

@ManeAFpod

NCCN Patient Resources for Breast Cancer
NCCN patient resources are based on the same treatment information your doctors use and help you talk to your doctor about the best treatment options for your disease.

National Cancer Institute: Breast Cancer in Men
The National Cancer Institute provides an overview of male breast cancer symptoms, diagnosis, treatment, genetic testing, and questions patients may want to discuss with their healthcare teams. The NCI notes that inherited variants in BRCA1, BRCA2, and other genes may influence treatment and have implications for relatives.

Facing Our Risk of Cancer Empowered (FORCE)
FORCE provides education, peer support, advocacy, research updates, and resources for people and families affected by inherited cancer risk, including BRCA1, BRCA2, PALB2, ATM, CHEK2, and other genes.

Find a Genetic Counselor
The National Society of Genetic Counselors’ (NSGC) directory can help patients locate a genetic counselor specializing in cancer genetics, either locally or through telehealth.

Cancer Genetic Testing
Genetic testing panels vary with how many genes are included. Healthcare providers can order just one gene or around a hundred, and everything in between. Tyler mentioned his possibly including 85, which is plausible. 

 

Relevant DNA Today Podcast Episode

#360 Hereditary Breast Cancer on the Big Screen with Love, Danielle
Actress and filmmaker Devin Sidell and hereditary cancer advocate Amy Byer Shainman discuss the film Love, Danielle, Devin’s experience with a BRCA1 pathogenic variant, hereditary breast cancer, preventive surgery, family communication, and using storytelling to increase awareness.

#364 Breast Cancer Genetic Testing in Italy: A Curated Gene Panel
This episode explores hereditary breast cancer testing, the genes included on breast cancer panels, and how researchers evaluate which genes have sufficient evidence to guide clinical care.

#159 Black Cancer Genes on Breast Cancer
Attorney and BRCA advocate Erika Stallings and genetic counselor Dena Goldberg discuss breast cancer genetics, BRCA1 and BRCA2, racial disparities in cancer genetics, and improving access to genetic counseling and testing in the Black community.

#165 Sequencing for Cancer Risk with Sandra Balladares
Scientist and breast cancer survivor Dr. Sandra Balladares shares her experience with breast cancer and discusses how genomic sequencing can identify inherited cancer risk, particularly within historically underserved populations.

#81 Irina Brooke on BRCA2
Patient advocate Irina Brooke shares her BRCA2 journey, including genetic counseling, genetic testing, cancer-risk management, and supporting people and families affected by hereditary cancer.

#25 Hereditary Cancer Syndromes with Ellen Matloff and Amy Byer Shainman
Hereditary cancer experts Ellen Matloff and Amy Byer Shainman discuss BRCA-associated cancer risks, genetic counseling, genetic testing, breast and ovarian cancer, and the documentary Pink & Blue, which includes the experiences of men affected by breast cancer.

 

Connect with DNA Today
You never have to wait long for a new episode of DNA Today, we release episodes every Friday! In the meantime, explore our library of over 400 episodes on Apple Podcasts, Spotify, DNAToday.com, or wherever you listen to podcasts. Just search “DNA Today.”

Prefer to watch? The video version of this episode is available on our YouTube channel and DNAToday.com. Select episodes are filmed in person, including some at the iconic NBCUniversal studios.

Discover more podcasts exploring genetics, genomics, medicine, and science from our network, Gene Pool Media: The Science Podcast Network.

DNA Today is hosted and executive produced by Kira Dineen, MS, LCGC, CG(ASCP)CM. Liv Davidson is our Social Media Lead and Eric Knaus is our Digital Marketing and Automation Lead. 

Follow us at @DNATodayPodcast on all platforms including Instagram, X, BluSky, Threads, LinkedIn, Facebook, YouTube and our website, DNAToday.com. 

Questions, partnership inquiries, and guest pitches can be sent to info@DNAToday.com.

Preparing for the genetic counseling board exam can feel overwhelming. Between the extensive study materials, challenging practice questions, and uncertainty about what to expect on exam day, candidates often struggle to determine where to begin and how to use their preparation time effectively.

In this episode of DNA Today, host Kira Dineen is joined by Melanie Hardy and Amy Shikany to explore the new and updated resources available to candidates preparing for the American Board of Genetic Counseling (ABGC) Certification Examination.

Melanie Hardy is the 2026 President of ABGC, and Amy Shikany is ABGC President-Elect and a past Chair of the Certification and Education Committee.

Together, they discuss ABGC’s Certify webpage, the new CGC self-study guide, the approved references list, a new student webinar, and the updated practice examination that launched on June 15, 2026. They also take listeners behind the scenes of how the certification exam is developed, reviewed, and maintained.

 

Discussion Topics:

What the ABGC Certification Examination is designed to assess

Where candidates should begin when navigating ABGC’s certification and exam resources

How to use the exam content outline when developing a study plan

Why ABGC created its new CGC self-study guide

How candidates can use the self-study guide alongside the approved references

What candidates can expect from ABGC’s new student webinar

How questions for the certification exam are written and reviewed

What makes a strong “one best answer” board-exam question

How ABGC evaluates questions for accuracy, relevance, fairness, and justice, equity, diversity, and inclusion considerations

What has changed in the updated ABGC practice examination

How closely the practice exam reflects the structure and reasoning required on the certification exam

How candidates should interpret their practice-exam results

How the passing standard for the certification exam is determined

Preparation steps candidates should take before exam day

Encouragement and next steps for candidates who do not pass on their first attempt

How certified genetic counselors can contribute to the development and maintenance of the examination

One clarification from the conversation: candidates are provided access to a simple calculator during the certification exam.

 

About the Guests
Melanie Hardy, MS, CGC is the 2026 President of the American Board of Genetic Counseling. Through her leadership with ABGC, she supports the organization’s work to establish and maintain certification standards for the genetic counseling profession and provide resources for current and future certified genetic counselors.

 

Amy Shikany, MS, CGC is President-Elect of the American Board of Genetic Counseling and a past Chair of ABGC’s Certification and Education Committee. Her work with ABGC has included supporting the development, review, and ongoing maintenance of the genetic counseling certification examination.

 

Resources Mentioned

American Board of Genetic Counseling (ABGC) website

Introducing the New CGC® Logo & Digital Badge

ABGC Certify 
Eligibility Requirements

Certification Process, Exam and Fees

Need-Based Certification Scholarship

ABGC CGC Exam Resources
Candidate Guide (Start here)

Exam Content Outline

Self Study Guide 
Syndromes and Disorders List on Pages 19 and 20

Practice Exam

Examination References 

Exam Performance Taskforce Report

Student Webinar (Coming Soon)

Relevant DNA Today Episodes:

#397 ABGC Recertification Changes: Learning Scenarios Explained for Genetic Counselors — Monica Marvin, Dr. Claire Davis, and Heather Rich explain ABGC’s new Continuing Competence Learning Scenarios, how the requirement fits into recertification, and what certified genetic counselors need to know.

#295 Genetic Counseling Board Exam Updates with ABGC — ABGC President Angela Trepanier and Executive Director Heather Rich provide an inside look at the certification exam, including exam development, scoring, administration, costs, financial assistance, equity, and available resources.

#235 Genetic Counseling History: ABGC Formation — Seasoned genetic counselors Ann Walker and Ed Kloza share about the formation of ABGC

#138 Genetic Counseling Boards Advice — Three genetic counselors share their experiences preparing for and taking the board exam, including study schedules, review courses, subject areas, resources, and balancing studying with work.

#126 Adam Buchanan on ABGC Boards Exam — Then-ABGC President Adam Buchanan answers listener questions about the exam’s structure, content, study resources, scoring, results, testing accommodations, cost, and inclusivity.

#57 Georgia Hurst on Lynch Syndrome — Patient advocate Georgia Hurst opens up about how Lynch syndrome has affected her and her family. This episode was mentioned towards the end of the interview. 

 

Connect:
Luckily you don’t have to wait long for a brand-new episode of DNA Today, we drop episodes every Friday! Until then, why not dive into our library of over 400 episodes? Binge them all on Apple Podcasts, Spotify, our website, or wherever you love to listen, just search “DNA Today.”

Prefer watching? We’ve got you covered! The video component of this episode is available on our YouTube channel and website. Some of these episodes were filmed at our home studio, the iconic NBC Universal Stamford Studios. 

DNA Today is hosted and produced by Kira Dineen, MS, LCGC, CG(ASCP)CM . Our Social Media Lead is Liv Davidson. Our Digital Marketing and Automation Lead is Eric Knaus. And the Graphic Designer of our logo is Ashlyn Enokian, MS, CGC. 

See what else we are up to on Instagram, X (Twitter), BluSky, Threads, LinkedIn, Facebook, YouTube and our website, DNAToday.com. Questions/inquiries can be sent to info@DNAtoday.com.

What happens when DNA from a decades-old crime scene meets a family tree created generations later?

That combination helped investigators identify the Golden State Killer and transformed how law enforcement approaches some of the country’s most difficult cold cases.

Content warning: This episode includes discussions of murder, sexual assault, suicide, and other sensitive topics.

In this episode of DNA Today, host Kira Dineen speaks with Paul Holes, a retired cold-case investigator, New York Times bestselling author, podcaster, and television host. During his 27-year career with the Contra Costa County Sheriff’s and District Attorney’s Offices, Paul worked on some of the most infamous cases in American criminal history, including the Zodiac murders, the kidnapping of Jaycee Dugard, and the investigation that ultimately identified Joseph DeAngelo as the Golden State Killer.

Paul is also the author of Unmasked: My Life Solving America’s Cold Cases, co-host of the podcast Small Town Dicks, and one of the investigators featured in the television special Celebrity Crime Scene: Marilyn Monroe, available on Hulu.

We explore the science, strategy, and ethical complexity behind cold-case investigations. Paul shares how investigators determine whether decades-old evidence still holds value, what kind of DNA evidence would be needed to scientifically resolve the Zodiac case, and why older biological samples create difficult decisions about whether to test now or preserve evidence for future technologies.

The episode also dives into the landmark investigation that identified the Golden State Killer. Paul walks through how traditional forensic DNA databases failed to produce a match, why investigative genetic genealogy changed the direction of the case, and how distant relatives’ DNA helped investigators build family trees that eventually led to Joseph DeAngelo.

Later in the episode, Paul discusses his latest project, Celebrity Crime Scene: Marilyn Monroe, and how modern virtual reconstruction can be used to reexamine a historic death scene more than six decades later.

Episode Discussion Topics

Cold-case investigations and how evidence is reexamined decades later

How investigators decide which biological samples may still have forensic value

The Zodiac Killer case and what would be needed to consider it scientifically solved

The challenges of DNA evidence from stamps, envelopes, letters, and other handled items

Why finite evidence creates difficult decisions about testing now versus waiting for future technology

The role of DNA in linking the Golden State Killer crimes before a suspect was identified

Why traditional forensic DNA databases did not solve the case

How investigative genetic genealogy helped generate a new lead

How distant relatives’ DNA can help identify someone who never uploaded their own DNA

The scientific and investigative process behind building genealogical trees from crime-scene DNA

How investigators narrowed family branches until Joseph DeAngelo became a viable suspect

Reconstructing Marilyn Monroe’s final hours using virtual crime-scene technology

What records, photographs, reports, and witness statements can reveal in historical case reviews

About Paul Holes
Paul Holes is a retired cold-case investigator, New York Times bestselling author, podcaster, and television host. During his 27-year career with the Contra Costa County Sheriff’s and District Attorney’s Offices, he investigated some of the country’s most complex and high-profile cases, including the Zodiac murders, the kidnapping of Jaycee Dugard, and the Golden State Killer case.

Paul’s work helped bring national attention to the power of investigative genetic genealogy, particularly through the identification of Joseph DeAngelo as the Golden State Killer. He is the author of Unmasked: My Life Solving America’s Cold Cases, co-host of Small Town Dicks, and appears in Celebrity Crime Scene: Marilyn Monroe.

Resources

Unmasked: My Life Solving America’s Cold Cases by Paul Holes

Small Town Dicks podcast

Celebrity Crime Scene: Marilyn Monroe, available on Hulu

Relevant DNA Today Podcast Episode
#326: How DNA Solves Crimes: The Forensic Science Behind True Crime

#131: DTC Series: Libby Copeland on Law Enforcement Use of Genetic Databases

#130 DTC Series: Anne Greb on 23andMe

Connect
Luckily you don’t have to wait long for a brand-new episode of DNA Today, we drop episodes every Friday! Until then, why not dive into our library of over 400 episodes? Binge them all on Apple Podcasts, Spotify, our website, or wherever you love to listen, just search “DNA Today.”

Prefer watching? We’ve got you covered! The video component of this episode is available on our YouTube channel and website. Some of these episodes were filmed at our home studio, the iconic NBC Universal Stamford Studios. 

DNA Today is hosted and produced by Kira Dineen, MS, LCGC, CG(ASCP)CM . Our Social Media Lead is Liv Davidson. Our Digital Marketing and Automation Lead is Eric Knaus. And the Graphic Designer of our logo is Ashlyn Enokian, MS, CGC. 

See what else we are up to on Instagram, X (Twitter), BluSky, Threads, LinkedIn, Facebook, YouTube and our website, DNAToday.com. Questions/inquiries can be sent to info@DNAtoday.com.